4-(tert-butyldimethylsiloxy)phenol CAS 108534-47-0

Description

Compared with other compounds in its class, the molecular weight of 230.42 g/mol gives 4-(tert-butyldimethylsiloxy)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

4-(tert-butyldimethylsiloxy)phenol (CAS 108534-47-0) is a high-purity analytical reference standard with the molecular formula C12H26O2Si and a molecular weight of 230.42 g/mol.

Structurally, 4-(tert-butyldimethylsiloxy)phenol (C12H26O2Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 0.0, corresponding to approximately 0 ring(s) or double-bond equivalent(s). With a molecular weight of 230.42 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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