4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid CAS 1086379-69-2
| CAS No. | 1086379-69-2 |
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid.
CATO supplies 4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid (CAS 1086379-69-2), a certified reference material (molecular formula C12H7F3N2O3, MW 284.19 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 3-((2-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid (CAS 1086379-72-7)
- 3-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)benzoic acid (CAS 1215846-99-3)
- 4-((6-(Trifluoromethyl)pyrimidin-4-yl)oxy)benzoic acid (CAS 1708288-98-5)
- 3-(3-(Trifluoromethyl)phenoxy)pyrazine-2-carboxylic acid (CAS 518057-62-0)
- 4-((4-(Trifluoromethyl)pyrimidin-2-yl)oxy)benzoic acid (CAS 914636-59-2)
- 4-Oxo-1-(3-(trifluoromethyl)phenyl)-1,4-dihydropyridazine-3-carboxylic acid (CAS 478063-68-2)
- Methyl 2-(((trifluoromethyl)sulfonyl)oxy)benzoate (CAS 17763-70-1)
- 3-{[5-methyl-3-(trifluoromethyl)-1h-pyrazol-1-yl]methyl}benzoic acid (CAS 1006348-88-4)
Recommended Standards
- 4-((2-Bromobenzyl)amino)cyclohexan-1-ol (CAS 1019495-87-4)
- Ethyl 3-cyano-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-5-carboxylate (CAS 1018142-98-7)
- 2-Bromo-N-ethyl-N-(m-tolyl)butanamide (CAS 1119450-24-6)
- 2-(4-Bromophenyl)-2,5,5-trimethylmorpholine (CAS 1017398-15-0)
- 3-(Morpholinomethyl)bicyclo[1.1.1]Pentan-1-amine (CAS 2303047-83-6)
- 5-PREGNEN-16, 17-EPOXY-3β, 21-DIOL-20-ONE 21-ACETATE (CAS 28444-97-5)
- 2-(4,5-Dimethylpyridin-3-yl)ethan-1-amine (CAS 1393545-20-4)
- 1-((1-(2-(Trifluoromethyl)pyrimidin-4-yl)piperidin-4-yl)methyl)pyrrolidin-2-one (CAS 123259-91-6)
- 5-Cyclopropoxynicotinic acid (CAS 1243368-67-3)
- (3,4,5-Tris(dodecyloxy)phenyl)methanol (CAS 138433-00-8)
- 5-chloro-1-methyl-1H-indole-2-carboxylic acid (CAS 59908-47-3)
- 2-(Chloromethyl)-3-(difluoromethyl)-5-methoxy-4-methylpyridine (CAS 1807018-18-3)
- 3-(Dimethylamino)quinazolin-4(3H)-one (CAS 5958-17-8)
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
Why CATO?
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