5-chloro-1-methyl-1H-indole-2-carboxylic acid CAS 59908-47-3
| CAS No. | 59908-47-3 |
| Molecular Formula | C10H16ClNO2 |
| Molecular Weight | 217.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-chloro-1-methyl-1H-indole-2-carboxylic acid (CAS 59908-47-3), molecular formula C10H16ClNO2 and molecular weight 217.69 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-chloro-1-methyl-1H-indole-2-carboxylic acid (C10H16ClNO2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 217.69 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-chloro-1-methyl-1H-indole-2-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H16ClNO2 |
| Molecular Weight | 217.69 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 2'-Chloro-6'-methyl-[1,1'-biphenyl]-4-amine (CAS 1044210-29-8)
- 3-(2-Chloro-pyridin-3-yl)-acrylic acid ethyl ester (CAS 104830-08-2)
- methyl 6-chloro-1H-indole-4-carboxylate (CAS 1082040-57-0)
- 2-Chloro-1-(octahydro-4H-benzo[b][1,4]oxazin-4-yl)ethan-1-one (CAS 1184627-66-4)
- 3'-Chloro-6-methyl-[1,1'-biphenyl]-3-amine (CAS 1208087-52-8)
- 2-Chloro-4'-methyl-biphenyl-4-ylamine (CAS 1208087-74-4)
- 3'-Chloro-4-methyl-[1,1'-biphenyl]-3-amine (CAS 1225957-41-4)
- methyl 5-chloro-1H-indole-7-carboxylate (CAS 1238214-63-5)
Recommended Standards
- 5-(Chloromethyl)-3-cyclohexyl-1,3-oxazolidin-2-one (CAS 26384-66-7)
- 5-Chloro-3-methyl-2-(o-tolyl)pyridine (CAS 2624417-46-3)
- 5-(4-Chlorophenyl)-2-methylaniline (CAS 244159-51-1)
- 5-Chloro-4-methyl-2-(o-tolyl)pyridine (CAS 2635937-69-6)
- N-(2-(5-amino-1,3,4-thiadiazol-2-yl)ethyl)-4-nitrobenzenesulfonamide (CAS 1199215-83-2)
- Allyl(3-isopropoxyphenyl)sulfane (CAS 1379358-99-2)
- (2-Methylenehexahydro-1H-pyrrolo[1,2-a]azepin-9a(5H)-yl)methanol (CAS 2829287-43-4)
- 4-Fluoro-3,5-dimethyl-1H-pyrazole-1-carboximidamide (CAS 764622-85-7)
- 1-(2-(Hydroxymethyl)pyrrolidin-1-yl)-2-phenylethan-1-one (CAS 124932-17-8)
- 5-Bromo-4-chloro-1H-indole (CAS 217656-69-4)
- Methyl 2-oxo-2,3-dihydrothiazole-4-carboxylate (CAS 56417-51-7)
- 2-allyl-2-fluoro-6-methylcyclohexan-1-one (CAS 122617-98-5)
- 3,9-Dibenzyl-3,7,9-triazabicyclo[3.3.1]nonane dihydrochloride (CAS 1630907-28-6)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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