2-Bromo-4-cyclopropylpyridine CAS 1086381-39-6
| CAS No. | 1086381-39-6 |
| Molecular Formula | C8H8BrN |
| Molecular Weight | 198.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Bromo-4-cyclopropylpyridine (C8H8BrN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromo-4-cyclopropylpyridine (CAS 1086381-39-6), molecular formula C8H8BrN and molecular weight 198.06 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-4-cyclopropylpyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8BrN |
| Molecular Weight | 198.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 3-Bromo-5-cyclopropylpyridine (CAS 1044210-57-2)
- 2-Bromo-6-cyclopropylpyridine (CAS 1086381-26-1)
- 4-Bromo-2-cyclopropylpyridine (CAS 1086381-28-3)
- 2-Bromo-6,7-dihydro-5H-cyclopenta[b]pyridine (CAS 1140240-18-1)
- 2-Bromo-5-cyclopropylpyridine (CAS 1142197-14-5)
- 2-Bromo-6-(prop-1-en-2-yl)pyridine (CAS 118775-68-1)
- 3-Bromo-5-(prop-1-en-2-yl)pyridine (CAS 118775-69-2)
- 2-Bromo-3-cyclopropylpyridine (CAS 1256788-23-4)
Recommended Standards
- Hydroxychloroquine EP Impurity G (CAS 86-98-6)
- 4,5-Dichloroquinoline (CAS 21617-18-5)
- (E)-4-(1-Bromoprop-1-en-2-yl)pyridine (CAS 1189785-29-2)
- 628-17-1 1-Iodopentane Pentane, 1-iodo- Amyl iodide n-Amyl iodide EINECS 211-030-0 1-Jodpentan [Czech] NSC 7901 Pentyl iodide n-Pentyl iodide 1-Pentyl iodide 1-Jodpentan (CAS 628-17-1)
- 4',2-Difluorobiphenyl-4-carboxamide (CAS 1214346-76-5)
- Ethyl 7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 438218-16-7)
- 1-Thia-2-azaspiro[3.3]heptane 1,1-dioxide (CAS 2383806-23-1)
- 1-(3-Ethylphenyl)butan-1-ol (CAS 676133-25-8)
- (S)-2-Aminobut-3-ynoic acid hydrochloride (CAS 1956434-80-2)
- Polyoxyethylene oleyl ether phosphate (CAS 39464-69-2)
- 5-Fluoro-2,4-bis((trimethylsilyl)oxy)pyrimidine (CAS 17242-85-2)
- Ethyl 5-(aminomethyl)imidazo[1,5-a]pyridine-1-carboxylate (CAS 1086392-80-4)
- Benzyl 2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 175137-29-8)
- Peptide 439 (CAS CATO-CPTD788439)
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