2-Bromo-5-ethylpyrazine CAS 1086382-74-2
| CAS No. | 1086382-74-2 |
| Molecular Formula | C6H7BrN2 |
| Molecular Weight | 187.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-ethylpyrazine.
CATO supplies 2-Bromo-5-ethylpyrazine (CAS 1086382-74-2), a certified reference material (molecular formula C6H7BrN2, MW 187.04 g/mol) for analytical method development and quality control.
2-Bromo-5-ethylpyrazine (C6H7BrN2) contains a nitrile group, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H7BrN2 |
| Molecular Weight | 187.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 6-Bromo-N-methylpyridin-3-amine (CAS 1022641-52-6)
- 3-Bromo-2,5-dimethylpyrazine (CAS 1035452-43-7)
- 4-Bromo-6-methylpyridin-3-amine (CAS 1060812-94-3)
- 4-Bromo-6-ethylpyrimidine (CAS 1086382-07-1)
- 2-Bromo-6-ethylpyrazine (CAS 1086382-92-4)
- 5-Bromo-2,3-dimethylpyrazine (CAS 111454-68-3)
- 4-Bromo-1-cyclopropyl-1H-pyrazole (CAS 1151802-23-1)
- 4-Bromo-2-cyclopropyl-1H-imidazole (CAS 1256790-50-7)
Recommended Standards
- 4-Bromopyridine-3-methanamine (CAS 1060805-63-1)
- 3-Bromopyridine-2-methanamine (CAS 1053053-92-1)
- 2-(2-Bromoethyl)pyrazine (CAS 1196093-34-1)
- 4-Amino-5-bromo-2-methylpyridine (CAS 10460-50-1)
- (2S,3S,4S)-Ethyl 3-(2-ethoxy-2-oxoethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylate (CAS 66163-47-1)
- N4-ETheno 2'-deoxycytidine (CAS 68498-26-0)
- 2-Amino-N'-phenyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carbohydrazide (CAS 861444-02-2)
- 6-Methoxy-2-pyridone (CAS 22385-36-0)
- 2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile (CAS 339010-55-8)
- tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate (CAS 227940-70-7)
- Dalpiciclib (CAS 1637781-04-4)
- 4-(Hydroxymethyl)-1-((tetrahydrofuran-2-yl)methyl)pyrrolidin-2-one (CAS 1017445-50-9)
- 3-((2-((2-Methylallyl)oxy)ethyl)amino)thietane 1,1-dioxide (CAS 1872958-52-5)
- Semaglutide impurity 76 (CAS CATO-C4X-222676)
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