2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile CAS 339010-55-8
| CAS No. | 339010-55-8 |
| Molecular Formula | C14H8ClF3N2 |
| Molecular Weight | 296.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 296.67 g/mol gives 2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile (CAS 339010-55-8), a certified reference material (molecular formula C14H8ClF3N2, MW 296.67 g/mol) for analytical method development and quality control.
The molecular framework of 2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile (C14H8ClF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-[6-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2-phenylacetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF3N2 |
| Molecular Weight | 296.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- Ethyl 2-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1h-pyrazol-1-yl)acetate (CAS 1002033-65-9)
- Methyl 3-(4-chloro-5-cyclopropyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)propanoate (CAS 1005583-79-8)
- Methyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-2-methylpropanoate (CAS 1354448-69-3)
- (2-Chloro-6-trifluoromethyl-pyridin-4-yl)-carbamic acid tert-butyl ester (CAS 1373223-18-7)
- 2-(2-(2-Chloro-4-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-07-8)
- 2-(2-(2-Chloro-5-(trifluoromethyl)phenoxy)ethyl)-1,3-dioxolane (CAS 1443303-77-2)
- Ethyl 3-(2-chloro-5-(trifluoromethyl)phenoxy)propanoate (CAS 1443303-84-1)
- Ethyl 3-(2-chloro-4-(trifluoromethyl)phenoxy)propanoate (CAS 1443345-65-0)
Recommended Standards
- 2-(4-Chlorophenyl)-3-(trifluoromethyl)benzofuran (CAS 821769-93-1)
- 5-Chloro-4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 931395-69-6)
- 2-(3-Chlorophenyl)-6-(trifluoromethyl)pyrazolo[1,5-a]pyridine (CAS 372122-59-3)
- 6-(4-Chlorophenyl)-2-methyl-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 200879-66-9)
- 1,3,7-trimethyl-6-oxo-1H,6H,7H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (CAS 1352534-55-4)
- Methyl 2,3-Dihydronaphtho[1,2-b]furan-3-acetate (CAS 2070896-68-1)
- 2-Chloro-N'-methyl-N'-(3-phenyl-6-(trifluoromethyl)-1,2,4-triazin-5-yl)acetohydrazide (CAS 672951-02-9)
- Methyl 2,4-dichloro-5-(difluoromethoxy)phenylacetate (CAS 1806328-98-2)
- 3-Fluoro-4-(methylsulfonyl)benzaldehyde (CAS 254878-95-0)
- 5-Amino-4-(1H-benzo[d]imidazol-2-yl)-1-(2-methoxybenzyl)-1,2-dihydro-3H-pyrrol-3-one (CAS 885189-72-0)
- 3-Hydroxy-2-phenylchroman-4-one (CAS 1621-55-2)
- 2.3-Peri-naphthylene-pyrene (CAS 188-89-6)
- (1-Fluorocyclopropyl)methyl 4-methylbenzenesulfonate (CAS 2104019-74-9)
- Tau Peptide (45-73) (Exon 2/Insert 1 Domain) trifluoroacetate salt (CAS 2022956-54-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com