n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide CAS 1087784-55-1
| CAS No. | 1087784-55-1 |
| Molecular Formula | C12H13ClFNO2 |
| Molecular Weight | 257.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (CAS 1087784-55-1), a certified reference material (molecular formula C12H13ClFNO2, MW 257.69 g/mol) for analytical method development and quality control.
The molecular framework of n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (C12H13ClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13ClFNO2 |
| Molecular Weight | 257.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related n Standards
- n-{2-[5-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (CAS 1384427-92-2)
- N-(2-Chloroacetyl)-L-tyrosine (CAS 1145-56-8)
- (2-Chloroacetyl)tyrosine (CAS 23965-60-8)
- Methyl 3-[3-(2-chloroacetyl)-2,5-dimethyl-1h-pyrrol-1-yl]propanoate (CAS 757219-83-3)
- n-[4-(2-chloroacetyl)-2-(methylsulfanyl)phenyl]acetamide (CAS 1146290-42-7)
- n-(2-Chloroacetyl)-3-(phenylthio)propanamide (CAS 565194-61-8)
- n-[5-(2-chloroacetyl)-2-(methylsulfanyl)phenyl]acetamide (CAS 874623-14-0)
- n'-(2-Chloroacetyl)-3-nitrobenzohydrazide (CAS 63002-52-8)
Recommended Standards
- 4-(2-Methyloxazol-4-yl)benzenesulfonyl chloride (CAS 1086376-81-9)
- (3-Phenyl-1,2-oxazol-5-yl)methanesulfonyl chloride (CAS 1087792-39-9)
- 2-Chloro-4-(4-fluorophenyl)quinoline (CAS 105189-21-7)
- (2-Chloro-6-fluorophenyl)(3-hydroxypiperidin-1-yl)methanone (CAS 1154909-89-3)
- N-methyl-1-(1-(tetrahydrofuran-3-yl)-1H-pyrazol-4-yl)methanamine (CAS 1340085-60-0)
- Dihydro-5-methyl-3(2H)-furanone (CAS 34003-72-0)
- 5-Bromo-8-methylquinolin-2(1H)-one (CAS 99455-07-9)
- 2-Methyleicosane (CAS 1560-84-5)
- (5-Fluoro-1h-1,3-benzodiazol-2-yl)methanamine dihydrochloride (CAS 1216862-84-8)
- Itopride Impurity 5 (CAS 3943-77-9)
- 3-(2,3-Dichlorophenyl)-1-propene (CAS 951892-37-8)
- 2-(tert-Butyl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2766177-70-0)
- 1,2-Diiodo-4,5-dimethoxybenzene (CAS 110190-08-4)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
Why CATO?
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