N-(2-Chloroacetyl)-L-tyrosine CAS 1145-56-8
| CAS No. | 1145-56-8 |
| Molecular Formula | C11H12ClNO4 |
| Molecular Weight | 257.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.67 g/mol gives N-(2-Chloroacetyl)-L-tyrosine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(2-Chloroacetyl)-L-tyrosine (CAS 1145-56-8), molecular formula C11H12ClNO4 and molecular weight 257.67 g/mol, is a CATO reference standard with documented purity and traceability.
N-(2-Chloroacetyl)-L-tyrosine (C11H12ClNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), N-(2-Chloroacetyl)-L-tyrosine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12ClNO4 |
| Molecular Weight | 257.67 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- (2-Chloroacetyl)tyrosine (CAS 23965-60-8)
- n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (CAS 1087784-55-1)
- n-{2-[5-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (CAS 1384427-92-2)
- Methyl 3-[3-(2-chloroacetyl)-2,5-dimethyl-1h-pyrrol-1-yl]propanoate (CAS 757219-83-3)
- n'-(2-Chloroacetyl)-3-nitrobenzohydrazide (CAS 63002-52-8)
- n'-(2-Chloroacetyl)-4-nitrobenzohydrazide (CAS 50677-28-6)
- n-[4-(2-chloroacetyl)-2-(methylsulfanyl)phenyl]acetamide (CAS 1146290-42-7)
- n-(2-Chloroacetyl)-3-(phenylthio)propanamide (CAS 565194-61-8)
Recommended Standards
- (5-Chloro-2-methoxybenzoyl)-L-alanine (CAS 1104730-93-9)
- Methyl ((7-chlorobenzo[d][1,3]dioxol-5-yl)methyl)glycinate (CAS 1152538-88-9)
- 3-Chloro-6-pivalamidopyridazine-4-carboxylic acid (CAS 1092286-27-5)
- 2-(4-Methyl-2-nitrophenoxy)butanoyl chloride (CAS 1160257-46-4)
- 6-(3,5-Dimethoxyphenyl)-6-oxohexanoic acid (CAS 52483-37-1)
- 3,3,3-Trifluoro-2,2-dimethylpropanimidamide (CAS 1217599-21-7)
- N-(5-(benzofuran-2-yl)-1,3,4-oxadiazol-2-yl)-4-((4-methylpiperidin-1-yl)sulfonyl)benzamide (CAS 922044-21-1)
- 5-Amino-1-(ethoxymethyl)pyrimidine-2,4(1h,3h)-dione (CAS 1489647-82-6)
- Pyridine-2,5-diol (CAS 84719-33-5)
- 1365962-70-4 2-Chloro-N-(2-chloro-4,6-dimethoxyphenyl)acetamide MFCD22056660 (CAS 1365962-70-4)
- 1-(2-Chloro-5-(trifluoromethyl)phenyl)-1H-pyrrole-2-carbaldehyde (CAS 299165-51-8)
- Cyclic acid (CAS 59564-78-2)
- N-benzyl-4-bromo-N-ethylbenzamide (CAS 346690-25-3)
- TAT 14 Peptide (Nrf2 Activator III) (CAS 1362661-34-4)
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