2-(Difluoromethoxy)acetic Acid CAS 1089695-61-3
| CAS No. | 1089695-61-3 |
| Molecular Formula | C3H4F2O3 |
| Molecular Weight | 126.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Difluoromethoxy)acetic Acid (CAS 1089695-61-3), molecular formula C3H4F2O3 and molecular weight 126.06 g/mol, is a CATO reference standard with documented purity and traceability.
2-(Difluoromethoxy)acetic Acid (C3H4F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Difluoromethoxy)acetic Acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H4F2O3 |
| Molecular Weight | 126.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
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Recommended Standards
- Ethephon-hydroxy (CAS 22987-21-9)
- 2,2-Difluoro-3-hydroxypropanoic acid (CAS 2368-37-8)
- Dimethyl Phosphate (CAS 813-78-5)
- 3,3-Difluoro-2-hydroxypropanoic acid (CAS 371961-43-2)
- 6-Bromo-7-methyl-1,8-naphthyridin-4-ol (CAS 151099-18-2)
- Ethyl 8-(3-chlorophenyl)-8-oxooctanoate (CAS 898752-20-0)
- 5-Bromo-1,3,3-trimethylindolin-2-one (CAS 72451-22-0)
- Methyl 5-bromo-4-chloro-2-iodobenzoate (CAS 1528948-34-6)
- Resmetirom impurity 108 (CAS CATO-C4X-2912108)
- 4-Methyl-1-(thiazol-2-yl)pentane-1,3-dione (CAS 1484589-69-6)
- 1-Bromo-3-(methylsulfanyl)propane (CAS 68731-27-1)
- (S)-2-(Methoxymethyl)pyrrolidine hydrochloride (CAS 95312-81-5)
- Midazolam Impurity 34 (CAS CATO-C4X-150934)
- Insulin Degludec Impurity 8 (CAS CATO-C4X-21578)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com