N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-6-(trifluoromethyl)pyridine-3-carbohydrazide CAS 1092346-16-1
| CAS No. | 1092346-16-1 |
| Molecular Formula | C18H11ClF4N4O3 |
| Molecular Weight | 442.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 442.75 g/mol gives N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-6-(trifluoromethyl)pyridine-3-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-6-(trifluoromethyl)pyridine-3-carbohydrazide (CAS 1092346-16-1), a certified reference material (molecular formula C18H11ClF4N4O3, MW 442.75 g/mol) for analytical method development and quality control.
N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-6-(trifluoromethyl)pyridine-3-carbohydrazide (C18H11ClF4N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H11ClF4N4O3 |
| Molecular Weight | 442.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 339106-67-1)
- 5-Chloro-N-(2,4-difluorophenyl)-2-oxo-1-(4-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 338977-82-5)
- 5-Chloro-N-(2,4-difluorophenyl)-6-oxo-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339024-18-9)
- 4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(methyl)amino)-5-methyl-2-(4-nitrobenzyl)-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 860786-15-8)
- N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2-[(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)oxy]acetamide (CAS 339096-77-4)
- 2-{N-[2-chloro-5-(trifluoromethyl)phenyl]methanesulfonamido}-N-(2,4-difluorophenyl)acetamide (CAS 478067-38-8)
- N-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-oxoethoxy)benzamide (CAS 303150-03-0)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-N-(4-methoxyphenyl)-1-methyl-1H-imidazole-5-carboxamide (CAS 339278-15-8)
Recommended Standards
- (S)-2-((1R,3aS,7aR,E)-4-((E)-2-((S)-5-((tert-butyldimethylsilyl)oxy)-2-methylenecyclohexylidene)ethylidene)-7a-methyloctahydro-1H-inden-1-yl)propanal (CAS 112828-12-3)
- Erythrodiol (CAS 545-48-2)
- 5-((4-Chlorophenyl)sulfonyl)-4-(2,4-dichlorophenyl)-N,N-dimethylpyrimidin-2-amine (CAS 339110-24-6)
- Betulin (CAS 473-98-3)
- 2-(chloromethyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole (CAS 1909337-19-4)
- 2-(4-Methoxyphenyl)isonicotinic acid (CAS 935861-30-6)
- 2-CHLORO-3-AMINO-5-BROMOPYRIDINE 3-AMINO-5-BROMO-2-CHLOROPYRIDINE 3-Amino-5-bromo-2-fluoropyridine 5-BROMO-2-CHLORO-3-AMINOPYRIDINE 5-BROMO-2-CHLORO-3-PYRIDINAMINE 5-BROMO-2-CHLORO-3-PYRIDYLAMINE 5-BROMO-2-CHLORO-PYRIDIN-3-YLAMINE 5-BROMO-2-CHLOROPYRIDIN-3-AMINE 884495-22-1 AF10133 (CAS 884495-22-1)
- (6-Methyl-2-phenyl-imidazo[1,2-a]pyridin-3-yl)-acetic acid (CAS 365213-66-7)
- 5-Deazaflavin (CAS 26908-38-3)
- 4-Ethoxy-N-(4-fluorobenzyl)aniline (CAS 356531-50-5)
- 2-Propyl-azetidine (CAS 89583-96-0)
- N-(4,6-dimethylpyridin-2-yl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)propanamide (CAS 478080-04-5)
- 6-Chloro-N-(2,2-dimethylthietan-3-yl)-2-methylpyrimidin-4-amine (CAS 1873431-64-1)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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