1-Benzyl-4-[6-(trifluoromethyl)pyridine-3-carbonyl]piperazine CAS 1092346-34-3
| CAS No. | 1092346-34-3 |
| Molecular Formula | C18H18F3N3O |
| Molecular Weight | 349.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Benzyl-4-[6-(trifluoromethyl)pyridine-3-carbonyl]piperazine (CAS 1092346-34-3), molecular formula C18H18F3N3O and molecular weight 349.35 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 1-Benzyl-4-[6-(trifluoromethyl)pyridine-3-carbonyl]piperazine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 349.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-Benzyl-4-[6-(trifluoromethyl)pyridine-3-carbonyl]piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H18F3N3O |
| Molecular Weight | 349.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Benzyl Standards
- 1-Methyl-4-{3-[5-(trifluoromethyl)pyridin-2-yl]benzoyl}piperazine (CAS 1092345-93-1)
- 1-Benzyl-4-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid (CAS 2329220-70-2)
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- 4-(4-(3-(Trifluoromethyl)phenyl)thiazol-2-yl)benzoic acid (CAS 321430-15-3)
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- 5-(Trifluoromethyl)-2-(3-(trifluoromethyl)-4,5,6,7-tetrahydro-1h-indazol-1-yl)aniline (CAS 937596-38-8)
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Recommended Standards
- 4-(((2,4-Diaminopteridin-6-yl)methyl)(prop-2-yn-1-yl)amino)benzoic acid (CAS 111854-71-8)
- 1-(6,7-Dimethoxyquinazolin-4-yl)-3-(pyridin-2-yl)-1H-1,2,4-triazol-5-amine (CAS 1080622-86-1)
- rel-(3S,4R)-1-Benzyl-4-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid (CAS 1263281-88-4)
- (S)-2-((S)-2-(2-Aminoacetamido)-3-(1H-imidazol-4-yl)propanamido)-3-(1H-imidazol-4-yl)propanoic acid (CAS 106644-04-6)
- 5-(2-Cyclohexenyl)-2-methylpyridine (CAS 1187163-28-5)
- Ethyl 3-[(5-chloro-2-fluorophenyl)amino]-2-cyanoprop-2-enoate (CAS 1181482-69-8)
- 2-(Aminomethyl)-6-fluoro-4-(trifluoromethyl)phenol (CAS 2050694-58-9)
- 2-Chloro-N-(2-methoxyethyl)pyrimidin-4-amine (CAS 1224600-39-8)
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- 6-Bromo-4-(p-tolyl)quinolin-2(1H)-one (CAS 1416440-34-0)
- 2-Bromo-N-(cyclohexylmethyl)acetamide (CAS 895244-78-7)
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