2-Chloro-3,5-difluoroaniline CAS 36556-60-2
| CAS No. | 36556-60-2 |
| Molecular Formula | C6H4ClF2N |
| Molecular Weight | 163.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 2-Chloro-3,5-difluoroaniline (CAS 36556-60-2), a certified reference material (molecular formula C6H4ClF2N, MW 163.55 g/mol) for analytical method development and quality control.
2-Chloro-3,5-difluoroaniline (C6H4ClF2N) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4ClF2N |
| Molecular Weight | 163.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1967 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-Chloro-6-(difluoromethyl)pyridine (CAS 1026587-36-9)
- 4-Chloro-2-(difluoromethyl)pyridine (CAS 1193104-11-8)
- 3-Chloro-5-(difluoromethyl)pyridine (CAS 1335055-92-9)
- 6-Chloro-2,3-difluoroaniline (CAS 1373920-77-4)
- 5-Chloro-2-(difluoromethyl)pyridine (CAS 1374659-32-1)
- 3-Chloro-4-(difluoromethyl)pyridine (CAS 1374659-44-5)
- 4-Chloro-3,5-difluoro-2-methylpyridine (CAS 139161-94-7)
- 3-Chloro-4,5-difluoroaniline (CAS 149144-05-8)
Recommended Standards
- 2-Chloro-3,4-difluoroaniline (CAS 36556-48-6)
- 2-Chloro-3,6-difluoroaniline (CAS 287172-80-9)
- 2-(Chloromethyl)-3,4-difluoropyridine (CAS 1805648-04-7)
- 2-Chloro-4,5-difluoroaniline (CAS 2613-32-3)
- tert-Butyl 2-oxo-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[indoline-3,4'-piperidine]-1'-carboxylate (CAS 1650548-34-7)
- (3-Chlorophenyl)(3-(2-((4-fluorobenzyl)oxy)phenyl)-1H-pyrazol-1-yl)methanone (CAS 477713-47-6)
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- 6-(2-Aminoethyl)-4-(trifluoromethyl)pyridin-2-amine (CAS 1393551-50-2)
- 2,5,8,10-Tetraoxatridec-12-enoicacid-9-oxo-2-propenyl ester (CAS 142-22-3)
- 8-Methyl-2-(4-methyl-3-nitrophenyl)imidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1215950-83-6)
- 2-(Benzyloxy)-5-nitrobenzaldehyde (CAS 204130-60-9)
- 5-Ethynyl-3-methoxythiophene-2-carbaldehyde (CAS 2314461-42-0)
- Hexapeptide-10 (CAS 146439-94-3)
Why CATO?
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