3-Chloro-4-(trifluoromethyl)cinnamic acid CAS 1092460-80-4
| CAS No. | 1092460-80-4 |
| Molecular Formula | C10H6ClF3O2 |
| Molecular Weight | 250.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-4-(trifluoromethyl)cinnamic acid (CAS 1092460-80-4), molecular formula C10H6ClF3O2 and molecular weight 250.60 g/mol, is a CATO reference standard with documented purity and traceability.
3-Chloro-4-(trifluoromethyl)cinnamic acid (C10H6ClF3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF3O2 |
| Molecular Weight | 250.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 3-(3-Chloro-2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)propanenitrile (CAS 1053658-44-8)
- 6-Chloro-7-(trifluoromethyl)chroman-4-one (CAS 1092349-68-2)
- (8-Chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl)methanol (CAS 1216024-49-5)
- 6-Chloro-8-(trifluoromethyl)chroman-4-one (CAS 1344889-75-3)
- (E)-3-(2-Chloro-5-(trifluoromethyl)phenyl)acrylic acid (CAS 1386504-00-2)
- 3-Chloro-5-(trifluoromethyl)cinnamic acid (CAS 1588508-15-9)
- 2-Chloro-4,4,4-trifluoro-1-phenylbutane-1,3-dione (CAS 163667-29-6)
- 4-Chloro-4,4-difluoro-1-(4-fluorophenyl)butane-1,3-dione (CAS 164342-74-9)
Recommended Standards
- Neodymium(III) chloride (CAS 10024-93-8)
- 2-(Difluoromethyl)-3-methyl-5-nitropyridine-4-carbonyl chloride (CAS 1807145-01-2)
- 3-(4-chlorophenyl)-4,4,4-trifluorobut-2-enoic acid (CAS 1394045-26-1)
- 6-(Difluoromethyl)-2-methyl-5-nitronicotinoyl chloride (CAS 1806999-80-3)
- 2-Methoxy-6,7-dihydro-5H-pyrrolo[3,4-d]pyrimidine (CAS 947305-13-7)
- 2-Ethoxyhexa-3,5-diene (CAS 56752-55-7)
- Propanoic acid, 3-[[bis(2-methylpropoxy)phosphinothioyl]thio]-2-methyl- (CAS 268567-32-4)
- 2-((3,4-Dichlorobenzyl)thio)-3-ethyl-5,6-dimethylthieno[2,3-d]pyrimidin-4(3H)-one (CAS 573670-02-7)
- (3-(Dimethylamino)imidazo[5,1-a]isoquinolin-1-yl)methanol (CAS 185016-97-1)
- {[5-(Trifluoromethyl)pyridin-2-yl]amino}acetic acid (CAS 923216-18-6)
- 2-(Bismethyl)aminomethylcyclohexanone-d (CAS 873928-71-3)
- 2-(1-Methyl-1H-pyrazol-4-yl)oxan-4-ol (CAS 1339529-08-6)
- Methyl 2-amino-5h,6h,7h-pyrrolo[1,2-a]imidazole-3-carboxylate (CAS 767316-84-7)
- D-Ser32-Tirzepatide (CAS CATO-CPTD788677)
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