5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine CAS 1092579-98-0

Purity 97%+In StockPharmaceutical Standards
CAS No.1092579-98-0
Molecular FormulaC8H4BrF3N2
Molecular Weight265.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine CAS 1092579-98-0 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 265.03 g/mol gives 5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1092579-98-0), molecular formula C8H4BrF3N2 and molecular weight 265.03 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine (C8H4BrF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-4-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC8H4BrF3N2
Molecular Weight265.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1989
Halogen ContentF/Br-containing
Nitrogen Atoms2

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