5-[(tert-Butyldimethylsilyl)oxy]-2-fluoro-3-(trifluoromethyl)phenol CAS 1881295-33-5
| CAS No. | 1881295-33-5 |
| Molecular Formula | C13H18F4O2Si |
| Molecular Weight | 310.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-[(tert-Butyldimethylsilyl)oxy]-2-fluoro-3-(trifluoromethyl)phenol is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-[(tert-Butyldimethylsilyl)oxy]-2-fluoro-3-(trifluoromethyl)phenol (CAS 1881295-33-5), a certified reference material (molecular formula C13H18F4O2Si, MW 310.36 g/mol) for analytical method development and quality control.
The molecular framework of 5-[(tert-Butyldimethylsilyl)oxy]-2-fluoro-3-(trifluoromethyl)phenol (C13H18F4O2Si) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-[(tert-Butyldimethylsilyl)oxy]-2-fluoro-3-(trifluoromethyl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H18F4O2Si |
| Molecular Weight | 310.36 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
Related tert Standards
- 1-(tert-butyldimethylsilyl)-6-bromo-1H-indole (CAS 184637-11-4)
- 2-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-6-fluoropyridine (CAS 1228666-47-4)
- tert-Butyldimethylsilyl N-Phenylbenzimidate (CAS 404392-70-7)
- 4-(3-((tert-Butyldimethylsilyl)oxy)propyl)-2-isopropylpyridin-3-amine (CAS 2641027-63-4)
- 3-((tert-Butyldimethylsilyl)oxy)-4-fluoro-N-methoxy-N-methylbenzamide (CAS 939399-42-5)
- 3-(4-((Tert-butyldimethylsilyl)oxy)-2-chlorophenyl)azetidin-3-ol (CAS 2166106-04-1)
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Recommended Standards
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- 1,1'-((Ethane-1,2-diylbis(azanediyl))bis(ethane-2,1-diyl))bis(2-amino-1H-imidazol-4(5H)-one) (CAS 98690-32-5)
- 1-Ethynyl-4-(heptyloxy)benzene (CAS 79887-18-6)
- Furo[2,3-b]pyridin-5-ol (CAS 181526-33-0)
- 4-Hydroxy-1,6-naphthyridine-3-carbonitrile (CAS 191287-56-6)
- 2-[[(2-methyl-4-thiazolyl)methyl]thio]-Acetic acid (CAS 446829-98-7)
- 4-Isopropoxy-3-methylphenol (CAS 1216201-65-8)
- 7-chloro-1,3-dihydroimidazo[4,5-b]pyridin-2-one (CAS 1202780-76-4)
- (6S)-6,7-Dihydro-5H-Pyrrolo[1,2-α]imidazol-6-amine HCl (CAS 1219019-28-9)
- 2-(2-(2-(5-Nitrofuran-2-yl)vinyl)benzamido)acetic acid (CAS 62113-77-3)
- 2-Thiaspiro[3.5]Nonan-7-amine (CAS 2060008-35-5)
- Peptide Impurity 06 (CAS CATO-CPTD788806)
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