Pirfenidone Impurity 27 CAS 109285-68-7
| CAS No. | 109285-68-7 |
| Molecular Formula | C6H7NO2 |
| Molecular Weight | 125.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Pirfenidone Impurity 27 is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Pirfenidone Impurity 27 (CAS 109285-68-7, C6H7NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Pirfenidone Impurity 27 (C6H7NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pirfenidone Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H7NO2 |
| Molecular Weight | 125.13 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 1 |
Related Pirfenidone Standards
- Pirfenidone Impurity 28 (CAS 856952-50-6)
- Pirfenidone Impurity 38 (CAS CATO-C4X-222938)
- Pirfenidone Impurity 39 (CAS 51566-22-4)
- Pirfenidone Impurity 16 (CAS CATO-C4X-222916)
- Pirfenidone Impurity 17 (CAS 126209-21-0)
- Pirfenidone Impurity 7 (CAS 501935-40-6)
- Pirfenidone Impurity 25 (CAS 2512237-43-1)
- Pirfenidone Impurity 40 (CAS CATO-C4X-222940)
Recommended Standards
- Cabozantinib Impurity 9 (CAS 3505-87-1)
- Metformin Impurity 19 (CAS CATO-C4X-122019)
- Relugolix Impurity 114 (CAS 89179-64-6)
- Metformin Impurity 18 (CAS 58228-69-6)
- Pivmecillinam Impurity 12 (CAS CATO-C4X-232312)
- Betaxolol Impurity 12 (CAS CATO-C4X-155912)
- Thiamine Impurity 32 (CAS 52164-53-1)
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- trans-3-(Benzyloxymethyl)cyclobutyl4-nitrobenzoate (CAS 172324-70-8)
- N-(azetidin-3-yl)-N-methylcyclopropanecarboxamide (CAS 1487174-32-2)
- N-(5-(Cyanomethyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 93355-73-8)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com