Metformin Impurity 18 CAS 58228-69-6

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.58228-69-6
Molecular FormulaC4H7N5
Molecular Weight125.13 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Metformin Impurity 18 CAS 58228-69-6 chemical structure

Description

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Metformin Impurity 18 (CAS 58228-69-6) is a certified pharmaceutical impurity reference standard with the molecular formula C4H7N5 and a molecular weight of 125.13 g/mol.

The molecular framework of Metformin Impurity 18 (C4H7N5) is characterized by a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

As a certified reference material (CRM), Metformin Impurity 18 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC4H7N5
Molecular Weight125.13 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1973
Nitrogen Atoms5

Related Metformin Standards

Recommended Standards

Why CATO?