methyl 6,6-difluorobicyclo[3.1.0]hexane-3-carboxylate CAS 1093750-99-2
| CAS No. | 1093750-99-2 |
| Molecular Formula | C8H10F2O2 |
| Molecular Weight | 176.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
methyl 6,6-difluorobicyclo[3.1.0]hexane-3-carboxylate (C8H10F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
methyl 6,6-difluorobicyclo[3.1.0]hexane-3-carboxylate (CAS 1093750-99-2) is a high-purity analytical reference standard with the molecular formula C8H10F2O2 and a molecular weight of 176.16 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H10F2O2 |
| Molecular Weight | 176.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
Related methyl Standards
- 7,7-Difluorobicyclo[2.2.1]Heptane-2-carboxylic acid (CAS 1432679-45-2)
- 2,2-Difluorobicyclo[2.2.1]heptane-1-carboxylic acid (CAS 2169578-23-6)
- 7,7-Difluorobicyclo[4.1.0]Heptane-1-carboxylic acid (CAS 2248351-67-7)
- (7,7-Difluorobicyclo[4.1.0]Heptan-3-yl)methanol (CAS 1494594-77-2)
- 6,6-difluorobicyclo[3.1.0]hexane-3-carboxylic acid (CAS 1093751-02-0)
- 8,8-Difluorobicyclo[3.2.1]octane-3-carboxylic acid (CAS 1447942-37-1)
- (3-exo)-8,8-Difluorobicyclo[3.2.1]octane-3-carboxylic acid (CAS 1447972-21-5)
- 5,6-Difluorobicyclo[2.2.1]Hept-2-Yl Acetate (CAS 162427-13-6)
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