Afoxolaner CAS 1093861-60-9
| CAS No. | 1093861-60-9 |
| Molecular Formula | C26H17ClF9N3O3 |
| Molecular Weight | 625.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Afoxolaner (CAS 1093861-60-9), a certified reference material (molecular formula C26H17ClF9N3O3, MW 625.87 g/mol) for analytical method development and quality control.
The molecular framework of Afoxolaner (C26H17ClF9N3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Afoxolaner meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H17ClF9N3O3 |
| Molecular Weight | 625.87 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Afoxolaner Standards
- Afoxolaner Impurity 32 (CAS CATO-C4X-313732)
- Afoxolaner Impurity 21 (CAS 1124305-96-9)
- Afoxolaner-d6 (CAS CATO-C4X-313725)
- Afoxolaner Impurity 22 (CAS 1125812-56-7)
- Afoxolaner Impurity 29 (CAS CATO-C4X-313729)
- Afoxolaner Impurity 30 (CAS CATO-C4X-313730)
- Afoxolaner Impurity 31 (CAS CATO-C4X-313731)
- Afoxolaner impurity 5 (CAS CATO-C4X-31375)
Recommended Standards
- N2-(1-Oxotetradecyl)-L-lysyl-L-alanyl-L-lysyl-L-alaninamide (CAS 959610-24-3)
- Fluralaner Impurity 26 (CAS 1096119-52-6)
- [S(R)]-N-[(R)-[3,5-Bis(1,1-dimethylethyl)-4-methoxyphenyl][2-(dicyclohexylphosphino)phenyl]methyl]-2-methyl-2-propanesulfinamide (CAS 2565792-75-6)
- Fluralaner Impurity 25 (CAS 1805814-97-4)
- Methyl (2S,5R)-2-isopropyl-1-methyl-3-oxo-2,3,4,5,6,8-hexahydro-1H-[1,4]diazonino[7,6,5-cd]indole-5-carboxylate (CAS 1097985-47-1)
- 5-fluoro-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1072009-08-5)
- 1-Propyl-1h-indol-6-amine (CAS 1095532-43-6)
- 5-Methoxy-2-methylpyrimidin-4-amine (CAS 698-34-0)
- 2-Butenedioic acid (2Z)-, 1,4-diethyl ester, polymer with chloroethene and ethenyl acetate (CAS 65072-38-0)
- Methyl 5-((N-methylsulfamoyl)methyl)-1H-indole-3-carboxylate (CAS 934236-31-4)
- 2-Oxepanone, polymer with 1,1'-methylenebis[4-isocyanatobenzene] (CAS 26761-25-1)
- Gibberellin A44 (CAS 36434-15-8)
- 2-Butenedioic acid (2E)-, polymer with 1,3-butadiene and 2-propenenitrile (CAS 33827-49-5)
- Allo-Thr7-Tirzepatide (CAS CATO-CPTD788933)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com