5-[4-(difluoromethoxy)phenyl]-1,2,4-triazin-3-amine CAS 1094271-28-9
| CAS No. | 1094271-28-9 |
| Molecular Formula | C10H8F2N4O |
| Molecular Weight | 238.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, 5-[4-(difluoromethoxy)phenyl]-1,2,4-triazin-3-amine (C10H8F2N4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 238.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
5-[4-(difluoromethoxy)phenyl]-1,2,4-triazin-3-amine (CAS 1094271-28-9), molecular formula C10H8F2N4O and molecular weight 238.19 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8F2N4O |
| Molecular Weight | 238.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related difluoromethoxy Standards
- 5-[2-(difluoromethoxy)phenyl]-1,2,4-triazin-3-amine (CAS 1094454-58-6)
- 1-(Difluoromethoxy)naphthalene-2-carboxylic acid (CAS 1261729-87-6)
- 4-(Difluoromethoxy)-1-naphthoic acid (CAS 1261884-90-5)
- 6-(Difluoromethoxy)-2-naphthoic acid (CAS 1261884-97-2)
- 3-(difluoromethoxy)naphthalene-2-carboxylic acid (CAS 929341-31-1)
- Methyl 3-(difluoromethoxy)-5-methoxythiophene-2-carboxylate (CAS 1710202-41-7)
- Ethyl 5-(difluoromethoxy)-4-fluoro-1-methyl-1H-pyrazole-3-carboxylate (CAS 1774902-68-9)
- Methyl 4-(difluoromethoxy)-2,6-difluorobenzoate (CAS 1040723-82-7)
Recommended Standards
- ISC-4 (CAS 1072807-15-8)
- 4,5,6,7,8-Pentahydroxy-2-oxooctanoic acid (CAS 1069-03-0)
- Methyl 5-(2,4-difluorophenyl)-1H-pyrazole-3-carboxylate (CAS 1119299-71-6)
- (2S,4R,5R)-2,4-Dihydroxy-5-((1R,2R)-1,2,3-trihydroxypropyl)tetrahydrofuran-2-carboxylic acid (CAS 105369-74-2)
- 4-Methyl-2-oxo-1,3-dioxane (CAS 17361-58-9)
- 4-Methyl-2-(methylthio)thiophen-3-amine (CAS 88246-46-2)
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