Empagliflozin Impurity 281 CAS 1096342-71-0
| CAS No. | 1096342-71-0 |
| Molecular Formula | C14H10BrClO |
| Molecular Weight | 309.59 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Empagliflozin Impurity 281 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Empagliflozin Impurity 281 (CAS 1096342-71-0) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10BrClO and a molecular weight of 309.59 g/mol.
Structurally, Empagliflozin Impurity 281 (C14H10BrClO) contains a hydroxyl group, an ether linkage, chlorine/bromine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 309.59 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H10BrClO |
| Molecular Weight | 309.59 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/Br-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 284 (CAS 1711323-05-5)
- Empagliflozin Impurity 130 (CAS 289039-54-9)
- Empagliflozin Impurity 63 (CAS 1360568-68-8)
- Empagliflozin Impurity 162 (CAS 1715629-30-3)
- Empagliflozin Impurity 172 (CAS CATO-C4X-1065172)
- Empagliflozin impurity 225 (CAS CATO-C4X-1065225)
- Empagliflozin Impurity 282 (CAS 1712958-06-9)
- Empagliflozin Impurity 151 (CAS 915095-85-1)
Recommended Standards
- 951891-16-0 4-Bromo-4'-chloro-3'-methylbenzophenone MFCD09801513 (CAS 951891-16-0)
- 4-Chloro-3-fluoro-3'-iodobenzophenone (CAS 951890-68-9)
- 4-Chloro-2-(pyrrolidin-1-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 1310384-39-4)
- 3-Bromo-4-chloro-3-methylbenzophenone (CAS 951891-14-8)
- Amisulpride Impurity 25 (CAS 483304-04-7)
- Suzetrigine Impurity 4 (CAS 2875067-17-5)
- Posaconazole Impurity 125 (CAS CATO-C4X-1208125)
- 1-(2-Bromophenyl)-4-oxocyclohexanecarboxylic Acid (CAS 1385694-47-2)
- Methyl 3-Bromo-5-chloro-1H-indazole-carboxylate (CAS 1352397-51-3)
- Furosemide Impurity 32 (CAS 18240-50-1)
- (S)-Benzyl pyrrolidin-3-ylcarbamate hydrochloride (CAS 1217631-74-7)
- p-Azidophenylglyoxal Monohydrate (CAS 1196151-49-1)
- 3-Nitro-2-(phenylsulfanyl)benzoic acid (CAS 13421-12-0)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com