1-Bromo-2,3-dichloro-4-methoxybenzene CAS 109803-52-3

Purity 97%+In StockPharmaceutical Standards
CAS No.109803-52-3
Molecular FormulaC7H5BrCl2O
Molecular Weight255.92 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-Bromo-2,3-dichloro-4-methoxybenzene CAS 109803-52-3 chemical structure

Description

The occurrence of 1-Bromo-2,3-dichloro-4-methoxybenzene is closely related to a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1-Bromo-2,3-dichloro-4-methoxybenzene (CAS 109803-52-3) is a high-purity analytical reference standard with the molecular formula C7H5BrCl2O and a molecular weight of 255.92 g/mol.

The molecular framework of 1-Bromo-2,3-dichloro-4-methoxybenzene (C7H5BrCl2O) is characterized by a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-Bromo-2,3-dichloro-4-methoxybenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H5BrCl2O
Molecular Weight255.92 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl/Br-containing

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