2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)aceticacid CAS 1098188-08-9
| CAS No. | 1098188-08-9 |
| Molecular Formula | C11H16F3NO4 |
| Molecular Weight | 283.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)aceticacid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)aceticacid (CAS 1098188-08-9), molecular formula C11H16F3NO4 and molecular weight 283.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)aceticacid (C11H16F3NO4) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16F3NO4 |
| Molecular Weight | 283.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
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