1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid CAS 887344-15-2
| CAS No. | 887344-15-2 |
| Molecular Formula | C11H16F3NO4 |
| Molecular Weight | 283.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 283.24 g/mol gives 1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 887344-15-2) is a high-purity analytical reference standard with the molecular formula C11H16F3NO4 and a molecular weight of 283.24 g/mol.
Structurally, 1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-3-carboxylic acid (C11H16F3NO4) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 283.24 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16F3NO4 |
| Molecular Weight | 283.24 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)aceticacid (CAS 1098188-08-9)
- 1-(tert-Butoxycarbonyl)-3-(trifluoromethyl)pyrrolidine-3-carboxylic acid (CAS 1260780-23-1)
- 2-((Tert-butoxycarbonyl)amino)-2-(trifluoromethyl)pent-4-enoic acid (CAS 1260807-59-7)
- 1-(tert-Butoxycarbonyl)-3,5,5-trifluoropiperidine-3-carboxylic acid (CAS 1823865-48-0)
- 2-((tert-Butoxycarbonyl)amino)-5-nitronicotinic acid (CAS 2248411-87-0)
- 2-((tert-Butoxycarbonyl)amino)-2-(dimethoxyphosphoryl)acetic acid (CAS 121056-96-0)
- 2-((tert-Butoxycarbonyl)(methyl)amino)-2-(4-fluorophenyl)acetic acid (CAS 1276112-08-3)
- 2-((tert-Butoxycarbonyl)amino)-3-(4-fluorophenyl)propanoic acid (CAS 129101-25-3)
Recommended Standards
- (S)-2-((tert-Butoxycarbonyl)amino)-2-(1-(trifluoromethyl)cyclopropyl)acetic acid (CAS 2407312-53-0)
- 1-(Tert-butoxycarbonylamino)-3-(trifluoromethyl)cyclobutanecarboxylicacid (CAS 2306270-08-4)
- (2S,4S)-1-(tert-Butoxycarbonyl)-4-(trifluoromethyl)pyrrolidine-2-carboxylic acid (CAS 470482-41-8)
- 1,4-Diamino-5-nitroanthracene-9,10-dione (CAS 82-33-7)
- 2-Ethoxy-N-(4-iodophenyl)benzamide (CAS 312588-69-5)
- 3-(3-Chloropropyl)-2-fluoro-4-iodopyridine (CAS 945600-05-5)
- 5,7-Docosadiynoic Acid (CAS 178560-65-1)
- 5-(1,2-Dihydroxyethyl)-3,4-dimethoxyfuran-2(5H)-one (CAS 40613-68-1)
- Bumetanide Impurity 96 (CAS 61658-51-3)
- 4-(Pyridin-4-yloxy)benzenesulfonicacid (CAS 192329-80-9)
- tert-Butyl ((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-3-yl)(ethyl)carbamate (CAS 1401666-89-4)
- 3-(Boc-amino)furan-2-carboxylic Acid (CAS 655255-06-4)
- Dimethyl (9H-carbazol-9-yl)phosphonate (CAS 865078-22-4)
- [2-31]-Semaglutide C (x TFA Salt) (CAS CATO-C4X-2226118)
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