1-Chloro-2,4-difluoro-3-(trifluoromethyl)benzene CAS 1099597-36-0
| CAS No. | 1099597-36-0 |
| Molecular Formula | C7H2ClF5 |
| Molecular Weight | 216.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Chloro-2,4-difluoro-3-(trifluoromethyl)benzene (CAS 1099597-36-0), molecular formula C7H2ClF5 and molecular weight 216.54 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine substitution, an aromatic ring system, 1-Chloro-2,4-difluoro-3-(trifluoromethyl)benzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 216.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H2ClF5 |
| Molecular Weight | 216.54 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 1-Chloro-2,5-difluoro-4-(trifluoromethyl)benzene (CAS 1099597-35-9)
- 2-Chloro-1,4-difluoro-3-(trifluoromethyl)benzene (CAS 1099597-70-2)
- 112290-03-6 2-Chloro-4,5-difluorobenzotrifluoride 8928AC C7H2ClF5 (CAS 112290-03-6)
- 1-Chloro-2,4-difluoro-5-(trifluoromethyl)benzene (CAS 115812-34-5)
- 2-Chloro-3,4-difluorobenzotrifluoride (CAS 119713-63-2)
- 2-Chloro-1,3-difluoro-4-(trifluoromethyl)benzene (CAS 120770-03-8)
- 1-Chloro-3,4-difluoro-2-(trifluoromethyl)benzene (CAS 1208076-15-6)
- 4-Chloro-2,6-difluorobenzotrifluoride (CAS 1221272-93-0)
Recommended Standards
- Sevoflurane Impurity 6 (CAS 26103-07-1)
- 1,1,2-Trifluoro-2-chloroethyl 2,2,2-Trifluoroethyl Ether (CAS 25364-98-1)
- (8-chloro-1-naphthyl)boronic acid (CAS 2305022-53-9)
- 2,4,6-Trichloroanisole-d5 (CAS 352439-08-8)
- (3Z)-N-(2,4-Dichlorophenyl)-3-{[(3,4-dichlorophenyl)methoxy]imino}propanamide (CAS 477851-46-0)
- 9-Bromo-2,4,7-trichloro-9H-fluorene (CAS 7012-19-3)
- 1-(But-3-yn-1-yl)piperidine-4-carboxylic acid (CAS 1156265-36-9)
- 1-(2,3-Dimethylphenyl)-6-mercapto-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1416339-45-1)
- (2-((2-Chlorophenoxy)methyl)phenyl)boronic acid (CAS 1256358-68-5)
- Poly[oxy(ethyl-1,2-ethanediyl)], .alpha.-(chlorocarbonyl)-.omega.-(tetrapropylenephenoxy)- (CAS 73467-77-3)
- (E)-2-(2,3-dihydro-1H-inden-1-ylidene)acetic acid (CAS 4709-52-8)
- 2-(Difluoromethyl)-4,5-dihydroxypyridine-3-acetic acid (CAS 1805007-23-1)
- Glufosinate (CAS 51276-47-2)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com