(8-chloro-1-naphthyl)boronic acid CAS 2305022-53-9

Purity 97%+In StockPharmaceutical Standards
CAS No.2305022-53-9
Molecular FormulaC10H18BClO2
Molecular Weight216.51 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(8-chloro-1-naphthyl)boronic acid CAS 2305022-53-9 chemical structure

Description

The occurrence of (8-chloro-1-naphthyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

(8-chloro-1-naphthyl)boronic acid (CAS 2305022-53-9) is a high-purity analytical reference standard with the molecular formula C10H18BClO2 and a molecular weight of 216.51 g/mol.

(8-chloro-1-naphthyl)boronic acid (C10H18BClO2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H18BClO2
Molecular Weight216.51 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityContains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)1.5
CAS Registry Year (est.)1999
Halogen ContentCl-containing

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