(2R)-2-amino-2-(3-chloro-4-methoxyphenyl)acetic acid CAS 109971-52-0
| CAS No. | 109971-52-0 |
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2R)-2-amino-2-(3-chloro-4-methoxyphenyl)acetic acid.
(2R)-2-amino-2-(3-chloro-4-methoxyphenyl)acetic acid (CAS 109971-52-0), molecular formula C9H10ClNO3 and molecular weight 215.63 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (2R)-2-amino-2-(3-chloro-4-methoxyphenyl)acetic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 215.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 2-Amino-2-(5-chloro-2-methoxyphenyl)acetic acid (CAS 1033583-97-9)
- Methyl 5-amino-2-chloro-4-methoxybenzoate (CAS 104253-47-6)
- Methyl 2-amino-3-chloro-4-methoxybenzoate (CAS 1180495-75-3)
- Methyl 2-amino-6-chloro-3-methoxybenzoate (CAS 1183040-46-1)
- 2-Amino-2-(7-chlorobenzo[d][1,3]dioxol-5-yl)ethan-1-ol (CAS 1183168-58-2)
- Methyl 2-amino-3-chloro-6-methoxybenzoate (CAS 1247590-21-1)
- Methyl 2-amino-4-chloro-3-methoxybenzoate (CAS 1249704-18-4)
- Methyl 2-amino-2-(3-chloro-4-hydroxyphenyl)acetate (CAS 1250501-73-5)
Recommended Standards
- 1-Chloro-2-(ethoxymethyl)-4-nitrobenzene (CAS 1097789-94-0)
- Ethyl 6-chloro-4-methoxypicolinate (CAS 1122090-80-5)
- 2-Chloro-6-isopropoxyisonicotinic acid (CAS 108994-42-9)
- Ethyl 5-chloro-4-methoxypicolinate (CAS 1122091-04-6)
- 2-(1H-Pyrazol-4-yl)benzo[d]thiazole (CAS 40142-85-6)
- 3-[(4-chloro-1h-pyrazol-1-yl)methyl]-4-methoxybenzaldehyde (CAS 895930-21-9)
- 1-Fluoro-2-(piperidin-4-yl)propan-2-ol hydrochloride (CAS 2608050-11-7)
- 3,4-Dimethyl-1-(1,3-dioxolan-2-ylmethyl)benzene (CAS 898759-39-2)
- N-(2-(Methylthio)phenyl)-3-oxo-2,3-dihydro-1H-indene-1-carboxamide (CAS 1207048-22-3)
- 4-Methoxy-N-(4-methoxyphenyl)benzamide (CAS 27865-44-7)
- 6-fluoropyridine-2-carbohydrazide hydrochloride (CAS 2031260-85-0)
- 5-Isopropylthiazole (CAS 16585-37-8)
- 3-Chloro-5-(trifluoromethyl)benzaldehyde (CAS 477535-43-6)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com