Methyl 2-amino-3-chloro-4-methoxybenzoate CAS 1180495-75-3
| CAS No. | 1180495-75-3 |
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Methyl 2-amino-3-chloro-4-methoxybenzoate (CAS 1180495-75-3), a certified reference material (molecular formula C9H10ClNO3, MW 215.63 g/mol) for analytical method development and quality control.
Structurally, Methyl 2-amino-3-chloro-4-methoxybenzoate (C9H10ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 215.63 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H10ClNO3 |
| Molecular Weight | 215.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- 2-Amino-2-(5-chloro-2-methoxyphenyl)acetic acid (CAS 1033583-97-9)
- Methyl 5-amino-2-chloro-4-methoxybenzoate (CAS 104253-47-6)
- (2R)-2-amino-2-(3-chloro-4-methoxyphenyl)acetic acid (CAS 109971-52-0)
- Methyl 2-amino-6-chloro-3-methoxybenzoate (CAS 1183040-46-1)
- 2-Amino-2-(7-chlorobenzo[d][1,3]dioxol-5-yl)ethan-1-ol (CAS 1183168-58-2)
- Methyl 2-amino-3-chloro-6-methoxybenzoate (CAS 1247590-21-1)
- Methyl 2-amino-4-chloro-3-methoxybenzoate (CAS 1249704-18-4)
- Methyl 2-amino-2-(3-chloro-4-hydroxyphenyl)acetate (CAS 1250501-73-5)
Recommended Standards
- N-[5-(2-Chloro-acetyl)-furan-2-ylmethyl]-acetamide (CAS 115865-57-1)
- 2-Chloro-3-(dimethoxymethyl)isonicotinaldehyde (CAS 1142192-52-6)
- Ethyl 5-chloro-4-methoxypicolinate (CAS 1122091-04-6)
- n-[(3-chloro-4,5-dimethoxyphenyl)methylidene]hydroxylamine (CAS 1195215-15-6)
- 4-[(2,4-Dichlorobenzyl)oxy]-3-iodobenzaldehyde (CAS 443123-69-1)
- 8-Benzyl-4-(naphthalene-2-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326809-22-6)
- (R)-1-Boc-amino-butyl-3-amine (CAS 1187927-71-4)
- Hexaphenylditin, 99+% (CAS 1064-10-4)
- Methyl 2,5-dichloro-3-methoxybenzoate (CAS 165377-90-2)
- 5-(Pyrimidin-5-yl)furan-2-carbaldehyde (CAS 342600-58-2)
- 3-ethylmorpholine (CAS 55265-24-2)
- 2′,4′,5′-Trimethoxyacetophenone (CAS 1818-28-6)
- (4-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-(trifluoromethyl)phenyl)methanone (CAS 898758-10-6)
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Why CATO?
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