[(2R,3R,5R)-5-(6-Aminopurin-9-yl-3-Fluorooxolan-2-Yl]Methanol CAS 110143-09-4
| CAS No. | 110143-09-4 |
| Molecular Formula | C10H12FN5O2 |
| Molecular Weight | 253.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including [(2R,3R,5R)-5-(6-Aminopurin-9-yl-3-Fluorooxolan-2-Yl]Methanol.
[(2R,3R,5R)-5-(6-Aminopurin-9-yl-3-Fluorooxolan-2-Yl]Methanol (CAS 110143-09-4) is a high-purity analytical reference standard with the molecular formula C10H12FN5O2 and a molecular weight of 253.23 g/mol.
Structurally, [(2R,3R,5R)-5-(6-Aminopurin-9-yl-3-Fluorooxolan-2-Yl]Methanol (C10H12FN5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 253.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), [(2R,3R,5R)-5-(6-Aminopurin-9-yl-3-Fluorooxolan-2-Yl]Methanol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FN5O2 |
| Molecular Weight | 253.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- ((2S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-fluorotetrahydrofuran-2-yl)methanol (CAS 110143-05-0)
- 6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine (CAS 110143-10-7)
- 5-((3-Nitro-1h-pyrazol-1-yl)methyl)thiophene-2-carboxylic acid (CAS 1006457-74-4)
- 1-[(4-nitrobenzene)sulfonyl]imidazole (CAS 110349-30-9)
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- 3-(6-Methyl-1H-indazol-3-yl)propan-1-amine (CAS 1545912-82-0)
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- 5-Chloro-3-(4-methoxy-phenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 1448694-38-9)
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