2-amino-6-chloro-pyridine-3-thiol CAS 110402-22-7
| CAS No. | 110402-22-7 |
| Molecular Formula | C5H11ClN2S |
| Molecular Weight | 166.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-amino-6-chloro-pyridine-3-thiol.
2-amino-6-chloro-pyridine-3-thiol (CAS 110402-22-7) is a high-purity analytical reference standard with the molecular formula C5H11ClN2S and a molecular weight of 166.67 g/mol.
Owing to sulfur-containing functionality, chlorine substitution, 2-amino-6-chloro-pyridine-3-thiol is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 166.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H11ClN2S |
| Molecular Weight | 166.67 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related amino Standards
- 2-amino-3-chloro-pyridine-4-thiol (CAS 2055759-39-0)
- 6-Amino-3-chloro-2-methylbenzonitrile (CAS 110127-06-5)
- 5-Amino-4-chloro-2-methylbenzonitrile (CAS 1173434-90-6)
- 2-(3-Amino-5-chlorophenyl)acetonitrile (CAS 1261470-81-8)
- 2-(3-Amino-4-chlorophenyl)acetonitrile (CAS 1261580-99-7)
- 4-Amino-3-chloro-5-methylbenzonitrile (CAS 158296-69-6)
- 7-Amino-3-chloro-1H-indole (CAS 165669-13-6)
- 2-(4-Amino-2-chlorophenyl)acetonitrile (CAS 180150-18-9)
Recommended Standards
- 1-Chloro-8-Fluorooctane (CAS 593-14-6)
- 2-chloro-5-methylsulfanyl-pyrimidine (CAS 115581-36-7)
- 3-Chloropropionaldehydediethylacetal(stabilized with K2CO3) (CAS 35573-93-4)
- Thioacetic Acid S-(3-Chloro-2-methyl-propyl) Ester (CAS 116008-86-7)
- Tert-butyl 4-(trifluoromethyl)piperidine-1-carboxylate (CAS 623165-99-1)
- n-(4-Chloro-1,3-dimethyl-1h-pyrazol-5-yl)methanesulfonamide (CAS 1497869-83-6)
- Tert-butyl 2-(piperidin-3-yl)acetate hydrochloride (CAS 1394040-19-7)
- N-(5-Amino-2-fluorophenyl)-2-(2-methylphenoxy)-butanamide (CAS 1020056-64-7)
- (R)-Propane-1,2-diamine sulfate (CAS 144118-44-5)
- 1-Methyl-4-((thietan-3-ylamino)methyl)piperidin-4-ol (CAS 1863314-19-5)
- L-NIL dihydrochloride (CAS 159190-45-1)
- Benzyl (4-aminobicyclo[2.1.1]hexan-1-yl)carbamate (CAS 1355004-67-9)
- Ethyl 4-(chloromethyl)nicotinate (CAS 94015-09-5)
- Semaglutide Impurity 115 (CAS CATO-C4X-2226115)
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