N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide CAS 1105235-63-9
| CAS No. | 1105235-63-9 |
| Molecular Formula | C21H13ClF3N3O2S |
| Molecular Weight | 463.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (C21H13ClF3N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 463.86 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105235-63-9), molecular formula C21H13ClF3N3O2S and molecular weight 463.86 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H13ClF3N3O2S |
| Molecular Weight | 463.86 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105207-34-8)
- 3-Chloro-2-({7-[(Z)-2-(4-methoxyphenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}sulfanyl)-5-(trifluoromethyl)pyridine (CAS 303150-40-5)
- 3-(5-Chloro-2-nitrophenyl)-1-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl)urea (CAS 1796905-13-9)
- Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3a',4',8',8a'-tetrahydrospiro[piperidine-4,6'-[1,3]dioxepino[5,6-d]isoxazole]-3'-carboxylate (CAS 303152-94-5)
- (((5-(2-Chloro-6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)phosphonic acid (CAS 2216763-68-5)
- 6-(5-Chloro-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazin-4-yl)-2-(1H-pyrrol-1-yl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carbonitrile (CAS 339279-35-5)
- 5-(5-((2-Chloro-8-methylquinolin-3-yl)methyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-5-oxopentanoic acid (CAS 361480-12-8)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477318-73-3)
Recommended Standards
- 3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-(3-fluorobenzyl)quinolin-4(1H)-one (CAS 1326845-99-1)
- ((2R,3R,4S,5R)-4-Acetoxy-5-(2-amino-6-chloro-9H-purin-9-yl)-3-fluorotetrahydrofuran-2-yl)methyl 4-methylbenzoate (CAS 1612192-25-2)
- (E)-N'-(Benzenesulfonyl)-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}morpholine-4-carboximidamide (CAS 318247-22-2)
- 1-Triacontylazide (CAS 1346603-49-3)
- 1-Methyl-3-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 478066-99-8)
- 2-((2-Chlorophenyl)thio)benzo[d]thiazole (CAS 60372-34-1)
- 5-Bromo-2-(difluoromethoxy)benzohydrazide (CAS 1403565-82-1)
- 3-(1H-Indol-2-yl)phenol (CAS 40756-70-5)
- 3-(Trifluoromethyl)benzylzinc chloride solution 0.5 M in THF (CAS 480438-42-4)
- (6-Methylquinolin-5-yl)methanamine (CAS 1211430-40-8)
- Benzyl 1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxylate (CAS 1097920-70-1)
- 1-(6-bromo-3-fluoropyridin-2-yl)ethan-1-ol (CAS 1403468-45-0)
- Cefoperazone Impurity 9 (CAS CATO-C4X-11499)
- Insulin Degludec Impurity 1 (CAS 843666-26-2)
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