3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-(3-fluorobenzyl)quinolin-4(1H)-one CAS 1326845-99-1
| CAS No. | 1326845-99-1 |
| Molecular Formula | C22H13ClF3NO3S |
| Molecular Weight | 463.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-(3-fluorobenzyl)quinolin-4(1H)-one (CAS 1326845-99-1) is a high-purity analytical reference standard with the molecular formula C22H13ClF3NO3S and a molecular weight of 463.86 g/mol.
Structurally, 3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-(3-fluorobenzyl)quinolin-4(1H)-one (C22H13ClF3NO3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 463.86 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-((3-Chlorophenyl)sulfonyl)-6,7-difluoro-1-(3-fluorobenzyl)quinolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H13ClF3NO3S |
| Molecular Weight | 463.86 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- Ethyl 4-[4-(4-chlorophenyl)piperazin-1-yl]-6-(trifluoromethyl)quinoline-3-carboxylate (CAS 338748-33-7)
- 1-((4-Chlorophenyl)sulfonyl)-4-(5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine (CAS 1073354-20-7)
- (3Z)-1-{[4-(3-chlorophenyl)piperazin-1-yl]methyl}-3-[2-(4-fluorophenyl)hydrazin-1-ylidene]-2,3-dihydro-1H-indol-2-one (CAS 338391-78-9)
- 3-((4-Chlorophenyl)sulfonyl)-N-(4-methylbenzyl)-[1,2,3]triazolo[1,5-a]quinazolin-5-amine (CAS 895646-91-0)
- N-(3-chlorophenyl)-3-((3,4-dichlorobenzyl)oxy)thieno[2,3-b]pyridine-2-carboxamide (CAS 338757-03-2)
- N-(4-Chlorophenyl)-3-[(3,4-dichlorophenyl)methoxy]thieno[2,3-b]pyridine-2-carboxamide (CAS 338756-88-0)
- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-isopropylphenyl)acetamide (CAS 476484-01-2)
- 2-((5-(((4-Chlorophenyl)amino)methyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N,N-diphenylacetamide (CAS 333314-33-3)
Recommended Standards
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105235-63-9)
- (E)-N'-(Benzenesulfonyl)-N-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}morpholine-4-carboximidamide (CAS 318247-22-2)
- N-[4-Chloro-3-(trifluoromethyl)phenyl]-2-{4-oxo-7-phenyl-3H,4H-thieno[3,2-d]pyrimidin-3-yl}acetamide (CAS 1105207-34-8)
- 3-Chloro-2-({7-[(Z)-2-(4-methoxyphenyl)ethenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl}sulfanyl)-5-(trifluoromethyl)pyridine (CAS 303150-40-5)
- N,N-Di-(7-methyloctyl)amine Hydrochloride (CAS 1246819-80-6)
- tert-Butyl 6-cyano-1,3-dihydro-2H-pyrrolo[3,4-c]pyridine-2-carboxylate (CAS 1823557-01-2)
- (Butan-2-yl)[(2-methoxyphenyl)methyl]amine (CAS 869942-65-4)
- 5-[2-(2-methylthiazol-4-yl)ethynyl]isoxazolo[5,4-b]pyridin-3-amine (CAS 2524947-36-0)
- 4-((5-Fluoro-2-methoxy-N-methylphenyl)sulfonamido)butanoic acid (CAS 697229-49-5)
- 4-(Methylthio)butanal (CAS 42919-64-2)
- 4-Aminothiophene-3-carboxamide (CAS 1629395-92-1)
- CAS 1427177-23-8 (CAS 1427177-23-8)
- 2-{[3-(4-chlorophenyl)-1,2-oxazol-5-yl]methyl}-2,3-dihydro-1H-isoindole-1,3-dione (CAS 478048-78-1)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com