Entecavir Impurity 25 CAS 110567-22-1
| CAS No. | 110567-22-1 |
| Molecular Formula | C20H22O3 |
| Molecular Weight | 310.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 310.39 g/mol gives Entecavir Impurity 25 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Entecavir Impurity 25 (CAS 110567-22-1, C20H22O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Entecavir Impurity 25 (C20H22O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Entecavir Impurity 25 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H22O3 |
| Molecular Weight | 310.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
Related Entecavir Standards
- Entecavir EP Impurity E (CAS 2349444-69-3)
- Entecavir Impurity 41 (CAS CATO-C4X-107741)
- Entecavir Impurity 81 (CAS CATO-C4X-107781)
- Entecavir Impurity 57 (CAS 84868-56-4)
- Entecavir Impurity 80 (CAS CATO-C4X-107780)
- Entecavir Impurity C182 (CAS 1984788-96-6)
- Entecavir Impurity 16 (Mixture of Diastereomers) (CAS CATO-C4X-107716)
- Entecavir EP Impurity C (CAS 2204369-23-1)
Recommended Standards
- 1-([1,1'-biphenyl]-2-yl(phenyl)methyl)-1H-imidazole (CAS CATO-C3D-6176)
- Palonosetron USP Related Compound B (CAS 1021456-82-5)
- 1-([1,1'-biphenyl]-3-yl(phenyl)methyl)-1H-imidazole (CAS CATO-C3D-26005)
- Netupitant Impurity 41 (CAS CATO-C4X-122341)
- Cefuroxime Impurity 78 (CAS CATO-C4X-124578)
- Olopatadine Impurity 32 (CAS CATO-C4X-171832)
- Perindopril Impurity 76 (CAS CATO-C4X-125276)
- 9-O-Methyl-isourolithin A (CAS 1460291-56-8)
- N-Boc-L-felinine (CAS 879207-98-4)
- 3-(2-(Trifluoromethyl)phenyl)acrylaldehyde (CAS 722549-18-0)
- 1,3-Bis((S)-1-(naphthalen-1-yl)ethyl)-1,3,2-diazaphospholidine 2-oxide (CAS 2166542-06-7)
- 3-{[(2-Chloro-acetyl)-cyclopropyl-amino]-methyl}-pyrrolidine-1-carboxylic acid benzyl ester (CAS 1353974-13-6)
- 3-Bromoisoxazol-5-amine (CAS 1446409-90-0)
- Galanin Message Associated Peptide (1-41) amide trifluoroacetate salt (CAS 132699-74-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com