5-Methoxy-N,4-dimethyl-N-phenylnicotinamide CAS 1105675-65-7
| CAS No. | 1105675-65-7 |
| Molecular Formula | C15H16N2O2 |
| Molecular Weight | 256.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Methoxy-N,4-dimethyl-N-phenylnicotinamide (CAS 1105675-65-7), molecular formula C15H16N2O2 and molecular weight 256.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Methoxy-N,4-dimethyl-N-phenylnicotinamide (C15H16N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), 5-Methoxy-N,4-dimethyl-N-phenylnicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H16N2O2 |
| Molecular Weight | 256.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 5-Methoxy-2-((4-methylbenzyl)oxy)benzaldehyde (CAS 1094563-34-4)
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- N-(5-chloro-2-methylphenyl)-2-(ethylamino)acetamide (CAS 500345-88-0)
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- 3-(Dimethylamino)-1-(4-methoxyphenyl)propan-1-ol (CAS 24221-38-3)
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