Tirzepatide Impurity 1 CAS 2460751-66-8
| CAS No. | 2460751-66-8 |
| Molecular Formula | C66H105N5O16 |
| Molecular Weight | 1224.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tirzepatide Impurity 1 (CAS 2460751-66-8, C66H105N5O16) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C66H105N5O16, Tirzepatide Impurity 1 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 1224.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tirzepatide Impurity 1 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C66H105N5O16 |
| Molecular Weight | 1224.56 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 5 |
Related Tirzepatide Standards
- Tirzepatide Impurity 18 (CAS CATO-C4X-324018)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
- Tirzepatide Impurity 17 (CAS CATO-C4X-324017)
- Tirzepatide Impurity 16 (CAS CATO-C4X-324016)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
- Tirzepatide Impurity 23 X TFA Salt (CAS CATO-C4X-324023)
Recommended Standards
- pGlu-His-L-Trp-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2 (CAS CATO-C4X-186235)
- Endotoxin Inhibitor (CAS 147396-10-9)
- Tyr-Bradykinin (CAS 33289-76-8)
- Cefpirome Impurity 40 (CAS CATO-C4X-120740)
- Timolol EP Impurity F (CAS 30165-96-9)
- Lorazepam Impurity 2 (CAS 773871-49-1)
- Glipizide Impurity 42 (CAS 73631-58-0)
- 1-Benzyl-2-isocyanatobenzene (CAS 146446-96-0)
- 6-Chlorocinnolin-4(1H)-one (CAS 18514-88-0)
- Methyl (1R,2S)-2-(4-bromophenyl)cyclopropane-1-carboxylate (CAS 1304688-84-3)
- 1-(4-Methoxyphenyl)-4-[(3-methylphenyl)sulfanyl]-2-phenyl-6,7-dihydro-1H-indole-5-carbaldehyde (CAS 477887-78-8)
- 3-Carboethoxy-3-(3-methoxyphenyl)propiophenone (CAS 898774-56-6)
- N-((3-(4-Methoxyphenyl)-2-oxooxazolidin-5-yl)methyl)thiophene-2-carboxamide (CAS 954648-38-5)
- D-[Thr]5-Semaglutide (CAS CATO-C4X-2226245)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com