4-Chloro-2-iodopyrimidine CAS 1108165-28-1
| CAS No. | 1108165-28-1 |
| Molecular Formula | C4H2ClIN2 |
| Molecular Weight | 240.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-2-iodopyrimidine.
4-Chloro-2-iodopyrimidine (CAS 1108165-28-1) is a high-purity analytical reference standard with the molecular formula C4H2ClIN2 and a molecular weight of 240.43 g/mol.
Based on its molecular formula C4H2ClIN2, 4-Chloro-2-iodopyrimidine contains a nitrile group, chlorine/iodine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 240.43 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-2-iodopyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H2ClIN2 |
| Molecular Weight | 240.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-5-iodopyrazine (CAS 1057216-55-3)
- 2-Chloro-6-iodopyrazine (CAS 120531-35-3)
- 5-Chloro-4-iodopyrimidine (CAS 1261473-90-8)
- 5-Chloro-3-iodopyridazine (CAS 1616070-38-2)
- 2-Chloro-3-iodopyrazine (CAS 191340-85-9)
- 2-Chloro-4-iodopyrimidine (CAS 395082-55-0)
- 2-Chloro-5-iodopyrimidine (CAS 32779-38-7)
- 4-Chloro-5-iodopyrimidine (CAS 63558-65-6)
Recommended Standards
- (Z)-Hexadec-11-en-1-ol (CAS 56683-54-6)
- Hexadecanal (CAS 629-80-1)
- tert-Butyldiphenylsilane (CAS 33729-92-9)
- Oxirane, 2-tetradecyl-, homopolymer (CAS 68110-12-3)
- 5-Methylpyridine-2-carboxaldehyde (CAS 4985-92-6)
- Methyl 5-bromo-4-(bromomethyl)nicotinate (CAS 2092466-35-6)
- 1-Methylethyl 2-amino-4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 929973-15-9)
- N-(cyclopropylmethyl)-1,3,4-thiadiazol-2-amine (CAS 1342764-93-5)
- Ethylamine Hydrochloride (CAS 557-66-4)
- 2-Ethyl-4,6-difluoro-2,3-dihydrobenzofuran-3-amine (CAS 1339889-18-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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