Alogliptin Impurity 3 CAS 1108731-49-2
| CAS No. | 1108731-49-2 |
| Molecular Formula | C20H23N5O3 |
| Molecular Weight | 381.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Alogliptin Impurity 3.
CATO supplies Alogliptin Impurity 3 (CAS 1108731-49-2), a pharmacopoeial impurity reference standard (molecular formula C20H23N5O3, MW 381.43 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Alogliptin Impurity 3 (C20H23N5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Alogliptin Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23N5O3 |
| Molecular Weight | 381.43 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
Related Alogliptin Standards
- Alogliptin impurity 85 (CAS CATO-C4X-109985)
- Alogliptin Impurity 43 (CAS 1618644-29-3)
- Alogliptin Impurity 9 (CAS CATO-C4X-10999)
- Alogliptin Impurity 62 (CAS 607376-86-3)
- Alogliptin impurity 88 (CAS 1473368-47-6)
- Alogliptin Impurity 19 (CAS CATO-C4X-109919)
- Alogliptin impurity 86 (CAS 2716884-59-0)
- Alogliptin Impurity 98 (CAS CATO-C4X-109998)
Recommended Standards
- Azilsartan Impurity 158 (CAS 183986-64-3)
- Oseltamivir Impurity 175 (CAS CATO-C4X-1720175)
- Tofacitinib Impurity 26 (CAS CATO-C4X-107926)
- Oseltamivir impurity 279 (CAS CATO-C4X-1720279)
- Aminolevulinic acid Impurity 1 (CAS 1781280-99-6)
- Trimebutine Impurity 21 (CAS CATO-C4X-185821)
- Dexamethasone impurity 89 (CAS CATO-C4X-116589)
- 5-Amino-4-(4-(3,4-dimethoxyphenyl)thiazol-2-yl)-1-phenyl-1,2-dihydro-3H-pyrrol-3-one (CAS 885460-77-5)
- 4-Chloro-N-(4-propoxybenzyl)aniline (CAS 1036585-50-8)
- (3-Ethylisoxazol-4-yl)methanol (CAS 1820651-17-9)
- 1-N-(1-Methylpiperidin-4-yl)benzene-1,2-diamine (CAS 600725-12-0)
- 6-Cyanoquinoxaline-2,3-dione (CAS 61875-40-9)
- 4-((4-(Diethylamino)-2-methylphenyl)imino)-N-methyl-1-oxo-1,4-dihydronaphthalene-2-carboxamide (CAS 102187-53-1)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com