Dexamethasone impurity 89 CAS CATO-C4X-116589
| CAS No. | CATO-C4X-116589 |
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Dexamethasone impurity 89 (CAS CATO-C4X-116589, C21H27FO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Dexamethasone impurity 89 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 362.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Dexamethasone impurity 89 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Impurity 33 (CAS 75262-69-0)
- Dexamethasone Impurity 85 (CAS CATO-C4X-116585)
- Dexamethasone Impurity 94 (CAS 59861-00-6)
- Dexamethasone EP Impurity E (CAS 13209-41-1)
- Dexamethasone Impurity 58 (CAS CATO-C4X-116558)
- Dexamethasone EP Impurity K (CAS 1809224-82-5)
- Dexamethasone EP Impurity J (CAS 2036-77-3)
- Dexamethasone EP Impurity D (CAS 24916-90-3)
Recommended Standards
- Nilotinib Impurity 13 (CAS CATO-C4X-125613)
- Febuxostat Impurity 73 (CAS 1346238-15-0)
- Betamethasone Impurity 128 (CAS CATO-C4X-1437128)
- Febuxostat Impurity 15 (CAS 1271738-74-9)
- Dacomitinib Impurity 38 (CAS CATO-C4X-208638)
- Apalutamide Impurity 57 (CAS CATO-C4X-274957)
- Amidotrizoate EP Impurity A (CAS 1713-07-1)
- 3-piperidin-3-yl-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepine (CAS 923164-14-1)
- 6-Chloro-3-fluoroisoquinoline (CAS 2386090-45-3)
- (S)-Tetrahydro-2H-pyran-2-amine hydrochloride (CAS 279683-11-3)
- Imidazo[2,1-b]thiazole-6-carbaldehyde (CAS 120107-61-1)
- Phenylpropiolic Acid (CAS 637-44-5)
- Ramipril Benzyl Ester-d5 (CAS 1356929-60-6)
- Semaglutide impurity 269 (CAS CATO-C4X-2226269)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com