N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide CAS 1108745-20-5
| CAS No. | 1108745-20-5 |
| Molecular Formula | C45H36F2N6O4 |
| Molecular Weight | 762.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 762.80 g/mol gives N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide (CAS 1108745-20-5), molecular formula C45H36F2N6O4 and molecular weight 762.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide (C45H36F2N6O4) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C45H36F2N6O4 |
| Molecular Weight | 762.80 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 6 |
Related N Standards
- N-(5-(3,5-Difluorobenzoyl)-1-trityl-1H-indazol-3-yl)-2,2,2-trifluoroacetamide (CAS 1108745-16-9)
- N-(5-(3,5-Difluorobenzoyl)-1H-indazol-3-yl)-4-(4-methylpiperazin-1-yl)-2-nitrobenzamide (CAS 1108745-22-7)
- N-((2,6-difluorobenzoyl)oxy)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338394-90-4)
- Methyl 4-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzoate (CAS 317833-48-0)
- 4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-45-7)
- 4-[(3,4-Difluorobenzoyl)Amino]-5-(3-Methoxypropyl-Pentylamino)-5-Oxopentanoic Acid (CAS 111106-23-1)
- 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775444-57-9)
- 3-[1-(2,5-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775544-13-2)
Recommended Standards
- 1,2-Dibromo-2-methylpropane (CAS 594-34-3)
- 2-hydroxy-2-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetamide (CAS 1421272-67-4)
- Diglutathionyl Mustard Phosphoramide (CAS 145784-68-5)
- (2S)-2-[[(2S)-2-[3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoylamino]-3-methyl-butanoyl]amino]propanoic acid (CAS 1800456-99-8)
- 2-Methyl-N-(tetrahydro-2h-thiopyran-3-yl)pyridin-3-amine (CAS 1514847-73-4)
- (Chloromethyl)dimethylsilanecarbonitrile (CAS 1964502-77-9)
- 4-Oxoundecanoic acid (CAS 22847-06-9)
- (1-Isobutyl-1H-pyrazol-3-yl)methanamine (CAS 1334492-60-2)
- Tert-butyl 3-bromo-5,6-dihydro-4H-imidazo[1,2-c][1,2,3]triazole-4-carboxylate (CAS 2169174-40-5)
- 2-(3-Bromophenyl)-8-chloroquinoline-4-carbonyl chloride (CAS 1160263-63-7)
- Isonicotinoyl chloride (CAS 14254-57-0)
- 2,7-Diazaspiro[4.4]nonan-1-one 2,2,2-trifluoroacetate (CAS 1956369-92-8)
- 2-(4-amino-5-fluoropentyl)guanidine (CAS 107240-29-9)
- Semaglutide Impurity 148 (CAS CATO-C4X-2226148)
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