4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one CAS 317833-45-7
| CAS No. | 317833-45-7 |
| Molecular Formula | C23H17F2N3O4 |
| Molecular Weight | 437.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-45-7), a certified reference material (molecular formula C23H17F2N3O4, MW 437.40 g/mol) for analytical method development and quality control.
4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one (C23H17F2N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(2,6-Difluorobenzoyl)-3-methyl-1-(4-nitrobenzyl)-3,4-dihydroquinoxalin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H17F2N3O4 |
| Molecular Weight | 437.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Difluorobenzoyl Standards
- 4-[(3,4-Difluorobenzoyl)Amino]-5-(3-Methoxypropyl-Pentylamino)-5-Oxopentanoic Acid (CAS 111106-23-1)
- 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775444-57-9)
- 3-[1-(2,5-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775544-13-2)
- 3-[1-(2,6-Difluorobenzoyl)piperidin-4-yl]-4-[(4-methoxyphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775561-05-1)
- Methyl 4-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzoate (CAS 317833-48-0)
- 4-(2,6-Difluorobenzoyl)-1-(3-methoxybenzyl)-3-methyl-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-52-6)
- 4-(2,6-Difluorobenzoyl)-1-[(4-methoxyphenyl)methyl]-3-methyl-1,2,3,4-tetrahydroquinoxalin-2-one (CAS 317833-54-8)
- 3-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-1,2,3,4-tetrahydroquinoxalin-1-yl]methyl}benzonitrile (CAS 317833-44-6)
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Why CATO?
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