5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine CAS 1111104-89-2
| CAS No. | 1111104-89-2 |
| Molecular Formula | C11H8F3N3 |
| Molecular Weight | 239.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 1111104-89-2), a certified reference material (molecular formula C11H8F3N3, MW 239.20 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-(Trifluoromethyl)phenyl)pyrimidin-2-amine (C11H8F3N3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8F3N3 |
| Molecular Weight | 239.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 2-(4-(Trifluoromethyl)phenyl)pyrimidin-5-amine (CAS 1094311-67-7)
- 5-(2-(Trifluoromethyl)phenyl)pyrimidin-2-amine (CAS 1111105-09-9)
- 6-(4-(Trifluoromethyl)phenyl)pyrazin-2-amine (CAS 1159819-32-5)
- 6-(4-(Trifluoromethyl)phenyl)pyridazin-3-amine (CAS 1215073-83-8)
- 5-(Trifluoromethyl)-[2,3'-bipyridin]-5'-amine (CAS 1255634-59-3)
- 6-(3-(Trifluoromethyl)phenyl)pyrimidin-4-amine (CAS 1482437-88-6)
- 2-(3-(Trifluoromethyl)phenyl)pyrimidin-5-amine (CAS 827322-74-7)
- 3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[3,4-a]isoquinoline (CAS 35515-45-8)
Recommended Standards
- 3-(6-Fluoro-2,3-dihydro-3-oxobenzo[b][1,4]oxazin-4-yl)propanoic Acid (CAS 1065678-56-9)
- 1,4-bis(3-chloropropyl)piperazine (CAS 27145-02-4)
- 3-(Pyridin-4-yl)-6-(trifluoromethyl)pyridin-2-amine (CAS 1214324-10-3)
- Ethyl 2-(trifluoroacetyl)-3-(N,N-dimethylamino)-2-propenoate (CAS 267243-86-7)
- 7-Morpholino-6-nitroquinazolin-4(3H)-one (CAS 66234-47-7)
- (E)-N-Cyclohexyl-N'-[(4-methylphenyl)methyl]-N''-phenylguanidine (CAS 338400-53-6)
- 3-((5-Methylhexyl)amino)thietane 1,1-dioxide (CAS 1882165-53-8)
- 6-Fluoro-1-methyl-1H-indazole (CAS 1209534-87-1)
- 3,4-Dichloro-5-iodopyridine (CAS 1806303-32-1)
- 4-Amino-4-(5-bromothiophen-2-yl)butanoic acid (CAS 1250224-42-0)
- 5-Bromo-1-cyclopentyl-1H-pyrazole (CAS 1368151-58-9)
- (1-Methylpyrrolidin-3-yl)methanamine dihydrochloride (CAS 1284226-96-5)
- 4-Methyl-2-(propan-2-yl)-1,3-thiazol-5-amine (CAS 1249718-43-1)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com