2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine CAS 1111319-86-8
| CAS No. | 1111319-86-8 |
| Molecular Formula | C22H19F2N5 |
| Molecular Weight | 391.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine.
2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine (CAS 1111319-86-8), molecular formula C22H19F2N5 and molecular weight 391.42 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine (C22H19F2N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 391.42 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H19F2N5 |
| Molecular Weight | 391.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Fluorophenyl Standards
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino 4-fluorobenzoate (CAS 338749-05-6)
- 1172045-66-7 4-[({[5-(3-Fluorophenyl)-2-thienyl]sulfonyl}amino)methyl]benzoic acid MFCD14281598 (CAS 1172045-66-7)
- (4-(2-Fluorophenyl)piperazin-1-yl)(4-(2-methylbenzoyl)-1H-pyrrol-2-yl)methanone (CAS 439120-85-1)
- 1-(2-Fluorophenyl)-3-(4-(4-(methylsulfonyl)phenyl)thiazol-2-yl)urea (CAS 882747-21-9)
- 4-(5-((5-(2-Fluorophenyl)furan-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)butanoic acid (CAS 890600-85-8)
- 1-(4-Fluorophenyl)-4-hydroxy-N-(2-(1-phenyl-1H-pyrazol-3-yl)ethyl)-1H-pyrazole-3-carboxamide (CAS 1798019-94-9)
- N-(2-((3-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)-2-phenylacetamide (CAS 946328-63-8)
- 2-((1-(4-Fluorophenyl)ethylidene)hydrazineylidene)-3-(furan-2-ylmethyl)-4-phenyl-2,3-dihydrothiazole (CAS 402945-83-9)
Recommended Standards
- 2,2'-(Azanediylbis(propane-3,1-diyl))bis(isoindoline-1,3-dione) (CAS 102202-87-9)
- (S)-1-((S)-2-Amino-5-guanidinopentanoyl)-N-(4-nitrophenyl)pyrrolidine-2-carboxamide (CAS 112898-06-3)
- Gatifloxacin Impurity 13 (CAS 103460-87-3)
- 2-((Chrysen-5-ylmethyl)amino)-1H-purin-6(9H)-one (CAS 117606-17-4)
- 2-(6-Chloro-5-(difluoromethyl)-4-(trifluoromethyl)pyridin-2-yl)acetonitrile (CAS 1805280-36-7)
- (2S,4R)-4-(Benzyloxy)-1-methylpyrrolidine-2-carboxylic acid (CAS 1131795-66-8)
- 3-(2-chloro-6-fluorophenyl)-4-[4-(4-chloro-3-nitrophenyl)-1,3-thiazol-2-yl]-5-methylisoxazole (CAS 287176-95-8)
- Methyl 2-acetamido-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate (CAS 328023-40-1)
- Sodium 2,6-dibromo-4-(3-(3,5-dibromo-4-hydroxy-2-methylphenyl)-1,1-dioxido-3H-benzo[c][1,2]oxathiol-3-yl)-3-methylphenolate (CAS 67763-24-0)
- 1265962-95-5 tert-Butyl 4-({[(2-methyl-1,3-thiazol-4-yl)methyl]amino}carbonyl)-1,3-thiazolidine-3-carboxylate MFCD15732219 (CAS 1265962-95-5)
- 2-((S)-2-((tert-Butoxycarbonyl)amino)-3-phenylpropanamido)-3-phenylpropanoic acid (CAS 112121-76-3)
- (3aR,6aR)-2,2-Dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-one (CAS 595581-64-9)
- 6-(4-(5-(Methoxymethyl)-2-oxooxazolidin-3-yl)phenyl)hexanenitrile (CAS 86405-72-3)
- Antistasin-Related Peptide (CAS 161561-46-2)
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