1-(4-Fluorophenyl)-4-hydroxy-N-(2-(1-phenyl-1H-pyrazol-3-yl)ethyl)-1H-pyrazole-3-carboxamide CAS 1798019-94-9
| CAS No. | 1798019-94-9 |
| Molecular Formula | C21H18FN5O2 |
| Molecular Weight | 391.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)-4-hydroxy-N-(2-(1-phenyl-1H-pyrazol-3-yl)ethyl)-1H-pyrazole-3-carboxamide.
1-(4-Fluorophenyl)-4-hydroxy-N-(2-(1-phenyl-1H-pyrazol-3-yl)ethyl)-1H-pyrazole-3-carboxamide (CAS 1798019-94-9) is a high-purity analytical reference standard with the molecular formula C21H18FN5O2 and a molecular weight of 391.40 g/mol.
1-(4-Fluorophenyl)-4-hydroxy-N-(2-(1-phenyl-1H-pyrazol-3-yl)ethyl)-1H-pyrazole-3-carboxamide (C21H18FN5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H18FN5O2 |
| Molecular Weight | 391.40 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
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- N-{4-[(4-fluorophenyl)sulfanyl]phenyl}-3-(trifluoromethyl)benzamide (CAS 339011-56-2)
- 2-(4-Fluorophenyl)-4-(4-(2-fluorophenyl)piperazin-1-yl)pyrazolo[1,5-a]pyrazine (CAS 1111319-86-8)
- 1172045-66-7 4-[({[5-(3-Fluorophenyl)-2-thienyl]sulfonyl}amino)methyl]benzoic acid MFCD14281598 (CAS 1172045-66-7)
- (4-(2-Fluorophenyl)piperazin-1-yl)(4-(2-methylbenzoyl)-1H-pyrrol-2-yl)methanone (CAS 439120-85-1)
- 1-(2-Fluorophenyl)-3-(4-(4-(methylsulfonyl)phenyl)thiazol-2-yl)urea (CAS 882747-21-9)
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Recommended Standards
- Zidebactam (CAS 1436861-97-0)
- N1-Mesityl-N1-((3-nitrophenyl)sulfonyl)oxalamide (CAS 188997-92-4)
- 2-Fluoro-5-[[5-[3-(4-morpholinyl)phenoxy]-2-pyrimidinyl]amino]benzonitrile (CAS 1350730-01-6)
- (((9H-Fluoren-9-yl)methoxy)carbonyl)(sulfo)-L-alanine (CAS 749820-65-3)
- Methyl octahydro-1H-indole-2-carboxylate (CAS 792888-27-8)
- 1-(Phenylamino)-N-(pyrrolidin-1-ylmethyl)cyclohexanecarboxamide (CAS 78349-36-7)
- [1,1′-Binaphthalene]-8,8′-dicarboxylic acid (CAS 29878-91-9)
- 6-(Bromomethyl)-2-pyridinemethanol (CAS 40054-01-1)
- 1-(4-Amino-3-iodo-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-2-methylpropan-2-ol (CAS 1951431-44-9)
- 1-Azabicyclo[2.2.1]heptane-7-carboxylic acid hydrochloride (CAS 646055-94-9)
- 2-(3,5-dimethylphenyl)cyclopentan-1-one (CAS 634603-16-0)
- 1-(5-Bromo-4-cyclopropylthiophen-2-yl)ethan-1-one (CAS 2302672-24-6)
- Carbetocin Impurity 13 (CAS CATO-C4X-191113)
- Biotinyl-Neuropeptide W-23 (human) (CAS 1815618-09-7)
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