7-(trifluoromethyl)chroman-4-one CAS 111141-02-7
| CAS No. | 111141-02-7 |
| Molecular Formula | C10H7F3O2 |
| Molecular Weight | 216.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-(trifluoromethyl)chroman-4-one is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 7-(trifluoromethyl)chroman-4-one (CAS 111141-02-7), a certified reference material (molecular formula C10H7F3O2, MW 216.16 g/mol) for analytical method development and quality control.
7-(trifluoromethyl)chroman-4-one (C10H7F3O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 7-(trifluoromethyl)chroman-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3O2 |
| Molecular Weight | 216.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related trifluoromethyl Standards
- 3-Oxo-3-(2-(trifluoromethyl)phenyl)propanal (CAS 1019029-43-6)
- 1-(4-(Trifluoromethyl)phenyl)propane-1,2-dione (CAS 10557-13-8)
- 1-(3-(Trifluoromethyl)phenyl)propane-1,2-dione (CAS 10557-15-0)
- 5-(Trifluoromethyl)chroman-4-one (CAS 111141-06-1)
- 6-(Trifluoromethyl)chroman-4-one (CAS 1122410-37-0)
- 2-(Trifluoromethyl)bicyclo[4.2.0]Octa-1,3,5-triene-7-carboxylic acid (CAS 1135489-35-8)
- 6-Trifluoromethyl-2,3-dihydro-1H-quinazolin-4-one (CAS 1220040-27-6)
- 7-(Trifluoromethyl)-2,3-dihydro-1,8-naphthyridin-4(1H)-one (CAS 1256786-51-2)
Recommended Standards
- 3-(3-(Trifluoromethoxy)phenyl)prop-2-yn-1-ol (CAS 1093173-10-4)
- 4-(Trifluoromethoxy)-2,3-dihydro-1H-inden-1-one (CAS 1083090-91-8)
- 3-(2-(Trifluoromethoxy)phenyl)prop-2-yn-1-ol (CAS 1141049-59-3)
- 1,2-Dihydro-3-methyl-1-oxo-7-(trifluoromethyl)pyrrolo[1,2-a]pyrazine (CAS 1025054-82-3)
- N-((5-bromothiophen-2-yl)methyl)thiophene-3-carboxamide (CAS 1100025-14-6)
- (S)-2-Amino-N-(3-methoxyphenyl)-3-phenylpropanamide (CAS 1217714-95-8)
- (R)-2-amino-2-(5-chloro-6-methoxypyridin-3-yl)ethan-1-ol (CAS 1213396-73-6)
- 4'-Ethoxy-2',3'-difluoro-4-propyl-2,3,4,5-tetrahydro-1,1'-biphenyl (CAS 1003218-25-4)
- 2-(tert-Butyl)-5-(chloromethyl)thiazole hydrochloride (CAS 861135-57-1)
- 3,4,5,6-Tetrachloropyridin-2-amine (CAS 51501-52-1)
- (S)-2,5-bis((tert-Butoxycarbonyl)(3-((tert-butoxycarbonyl)amino)propyl)amino)pentanoic acid (CAS 119798-08-2)
- Posaconazole lmpurity 179 (CAS CATO-C4X-1208179)
- 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338770-35-7)
- Insulin Degludec Impurity 12 (CAS CATO-C4X-215712)
Why CATO?
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