1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione CAS 338770-35-7
| CAS No. | 338770-35-7 |
| Molecular Formula | C23H18ClF6N5O3 |
| Molecular Weight | 561.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 338770-35-7) is a high-purity analytical reference standard with the molecular formula C23H18ClF6N5O3 and a molecular weight of 561.86 g/mol.
The molecular framework of 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione (C23H18ClF6N5O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-3-methyl-5-[(2E)-3-{[4-(trifluoromethyl)phenyl]amino}prop-2-enoyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H18ClF6N5O3 |
| Molecular Weight | 561.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Related chloro Standards
- Methyl 6-chloro-1-naphthoate (CAS 5471-30-7)
- 1-Des(3-chloro-2-pyridinyl)-1-(3-chloro-5-bromo-2-pyridinyl)chlorantraniliprole (CAS 500011-53-0)
- 3-Chloro-2-[(Z)-2-(1-{3-[(4-chlorobenzenesulfonyl)methyl]-4-nitrophenyl}ethylidene)-1-methylhydrazin-1-yl]-5-(trifluoromethyl)pyridine (CAS 339016-36-3)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(4-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1H-pyrrole-2-carboxamide (CAS 338397-67-4)
- N-(3-chloro-4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-carboxamide (CAS 338397-72-1)
- 3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxyphenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide (CAS 338777-57-4)
- Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-3-(1,3-dioxo-2,3-dihydro-1H-inden-2-ylidene)-4,6-dioxo-octahydropyrrolo[3,4-c]pyrrole-1-carboxylate (CAS 321522-13-8)
- 5-Chloro-6-iodo-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1357387-50-8)
Recommended Standards
- 2-{N-[2,4-dichloro-5-(2-methoxyethoxy)phenyl]4-chlorobenzenesulfonamido}-N-(4-fluorophenyl)acetamide (CAS 338967-64-9)
- 3,6-Diiodo-2-(5-iodofuran-2-yl)imidazo[1,2-a]pyridine (CAS 61982-67-0)
- (S)-2-((Bis(tetradecyloxy)phosphoryl)amino)propanoic acid (CAS 830320-80-4)
- 14-Chlorodaunorubicin (CAS 121250-06-4)
- (R)-2-Amino-2-(1,4-dimethyl-1H-pyrazol-5-yl)ethan-1-ol (CAS 1641033-82-0)
- (S)-4-(iodomethyl)-2,2-dimethyl-1,3-dioxolane 2,2-Dimethyl-4(S)-4-iodomethyl-1,3-dioxalane 23735-44-6 (CAS 23735-44-6)
- Heptyl propionate (CAS 2216-81-1)
- (3-Tert-butyl-1,2,4-oxadiazol-5-yl)methanol (CAS 1153757-34-6)
- 4-Methyl-N-(5-(((2-methylthiazol-4-yl)methyl)thio)-1,3,4-thiadiazol-2-yl)thiophene-2-carboxamide (CAS 1351590-83-4)
- 2-(4-Isobutylphenyl)-6-methylquinoline-4-carboxylic acid (CAS 438219-40-0)
- 4,6-Dibromo-2-nitrobenzene-1,3-diol (CAS 17427-85-9)
- 2-Amino-1-methyl-4,5-dihydro-1H-imidazole-4,5-dicarbonitrile (CAS 644996-56-5)
- Formaldehyde, polymer with 6-phenyl-1,3,5-triazine-2,4-diamine and 1,3,5-triazine-2,4,6-triamine (CAS 25035-72-7)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com