Tobramycin Impurity N2 CAS 111170-72-0
| CAS No. | 111170-72-0 |
| Molecular Formula | C6H14N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tobramycin Impurity N2.
As a process- or degradation-related impurity, Tobramycin Impurity N2 (CAS 111170-72-0, C6H14N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Tobramycin Impurity N2 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 198.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tobramycin Impurity N2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H14N2O3 2*HCl |
| Molecular Weight | 198.65 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tobramycin Standards
- Tobramycin Sulfate (CAS 126777-32-0)
- Tobramycin Impurity 2 (CAS 1488363-39-8)
- Tobramycin Impurity 13 HCl (CAS 19309-98-9 (free base))
- Tobramycin Impurity 15 (CAS 207670-58-4)
- Tobramycin (CAS 32986-56-4)
- Tobramycin 5/2sulfate (CAS 49842-07-1)
- Tobramycin Impurity N1 (CAS 51736-77-7)
- Tobramycin Impurity 12 xHAc (CAS 51736-77-7(free base))
Recommended Standards
- Dotinurad Impurity 131 (CAS CATO-C4X-2494131)
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- 4-(4-Bromophenoxy)phenol (CAS 13320-48-4)
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- Benzyl (S)-1-(fluoromethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)cyclohex-3-ene-1-carboxylate (CAS 1818868-50-6)
- [Plus-β-Ala28]-Semaglutide (CAS CATO-C4X-2226221)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com