Tenofovir disoproxil Impurity 28 CAS 1115-59-9
| CAS No. | 1115-59-9 |
| Molecular Formula | C5H11NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tenofovir disoproxil Impurity 28 (CAS 1115-59-9), a pharmacopoeial impurity reference standard (molecular formula C5H11NO2HCl, MW 153.61 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Tenofovir disoproxil Impurity 28 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 153.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tenofovir disoproxil Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H11NO2 HCl |
| Molecular Weight | 153.61 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
- Tenofovir disoproxil Impurity 4 (CAS 1217542-13-6(Free base))
Recommended Standards
- Carteolol Impurity 26 (CAS 594-70-7)
- Nalmefene Impurity 6 (CAS CATO-C4X-12686)
- Clindamycin Phosphas Impurity 46 (CAS CATO-C4X-134146)
- (R)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid (CAS 415898-69-0)
- 5-Carbamoylnicotinic acid (CAS 24242-17-9)
- 1-((5-Ethyl-1,2,4-oxadiazol-3-yl)methyl)-1H-pyrazole-3-carboxylic acid (CAS 1342420-52-3)
- 2-(Furan-3-ylmethylene)hydrazinecarbothioamide (CAS 848030-64-8)
- 4-Chloro-3-phenyl-6-{[3-(trifluoromethyl)phenyl]sulfanyl}pyridazine (CAS 477872-32-5)
- 2-(2-Fluoro-4-nitrophenoxy)acetohydrazide (CAS 1339073-38-9)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com