(Z)-3-(Thiazol-4-yl)acrylonitrile CAS 111601-02-6

Purity 97%+In StockPharmaceutical Standards
CAS No.111601-02-6
Molecular FormulaC6H4N2S
Molecular Weight136.17 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(Z)-3-(Thiazol-4-yl)acrylonitrile CAS 111601-02-6 chemical structure

Description

The molecular framework of (Z)-3-(Thiazol-4-yl)acrylonitrile (C6H4N2S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

CATO supplies (Z)-3-(Thiazol-4-yl)acrylonitrile (CAS 111601-02-6), a certified reference material (molecular formula C6H4N2S, MW 136.17 g/mol) for analytical method development and quality control.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (Z)-3-(Thiazol-4-yl)acrylonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4N2S
Molecular Weight136.17 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Nitrogen Atoms2
Sulfur Atoms1

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