3-(Thiazol-5-yl)propanenitrile CAS 1248546-18-0
| CAS No. | 1248546-18-0 |
| Molecular Formula | C6H6N2S |
| Molecular Weight | 138.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-(Thiazol-5-yl)propanenitrile (CAS 1248546-18-0), a certified reference material (molecular formula C6H6N2S, MW 138.19 g/mol) for analytical method development and quality control.
The molecular framework of 3-(Thiazol-5-yl)propanenitrile (C6H6N2S) is characterized by a nitrile group, sulfur-containing functionality, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6N2S |
| Molecular Weight | 138.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Thiazol Standards
- 2-(1,3-thiazol-2-yl)propanenitrile (CAS 101010-75-7)
- (5-Methyl-1,3-thiazol-2-yl)acetonitrile (CAS 851269-14-2)
- 2-(4-Methyl-1,3-thiazol-5-yl)acetonitrile (CAS 50382-33-7)
- (E)-3-(Thiazol-4-yl)acrylaldehyde (CAS 185947-65-3)
- 1-(Thiazol-2-yl)prop-2-yn-1-ol (CAS 271597-72-9)
- (E)-3-(Thiazol-4-yl)acrylonitrile (CAS 111601-01-5)
- (Z)-3-(Thiazol-4-yl)acrylonitrile (CAS 111601-02-6)
- 1-Thiazol-5-yl-cyclopropylamine (CAS 1503945-34-3)
Recommended Standards
- N-Acetyl-d3-glycine-d2 N-Methyl-d3-amide (CAS 1219802-57-9)
- n-(Prop-2-yn-1-yl)-1,3-thiazol-2-amine (CAS 1250676-92-6)
- 2,4-Dimethylthiazole-5-carbonitrile (CAS 1215959-36-6)
- 3-Sulfanylbenzaldehyde (CAS 129747-73-5)
- 5-(3-Chlorophenyl)-4-phenyl-4h-1,2,4-triazole-3-thiol (CAS 93717-11-4)
- Tenuifolin (CAS 20183-47-5)
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- 8-(Tert-butoxycarbonyl)-1,8-diazaspiro[4.5]Decane-2-carboxylic acid (CAS 1779479-75-2)
- methyl 4-oxo-1,2,3,3a,4,5-hexahydropyrrolo[1,2-a]quinoxaline-7-carboxylate (CAS 860189-19-1)
- N1-(2,2-Dimethoxyethyl)-N2-(2-fluorophenyl)oxalamide (CAS 898356-30-4)
- 2-(Isopropylamino)-4-(2-methyl-1h-imidazol-1-yl)butanamide (CAS 1342044-07-8)
- n-{6-oxaspiro[4.5]decan-9-yl}methanesulfonamide (CAS 1423634-82-5)
- (4AR,6S,7R,8S,8aS)-8-(allyloxy)-7-(benzyloxy)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxine (CAS 1203549-89-6)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
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