3-((4-Methoxy-N-methylphenyl)sulfonamido)-N-(3-methoxybenzyl)thiophene-2-carboxamide CAS 1116082-60-0
| CAS No. | 1116082-60-0 |
| Molecular Formula | C21H22N2O5S2 |
| Molecular Weight | 446.54 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 446.54 g/mol gives 3-((4-Methoxy-N-methylphenyl)sulfonamido)-N-(3-methoxybenzyl)thiophene-2-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-((4-Methoxy-N-methylphenyl)sulfonamido)-N-(3-methoxybenzyl)thiophene-2-carboxamide (CAS 1116082-60-0), molecular formula C21H22N2O5S2 and molecular weight 446.54 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 3-((4-Methoxy-N-methylphenyl)sulfonamido)-N-(3-methoxybenzyl)thiophene-2-carboxamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.54 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H22N2O5S2 |
| Molecular Weight | 446.54 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related Methoxy Standards
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- (E)-2-{3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl}-N-[(thiophen-2-yl)methyl]ethene-1-sulfonamide (CAS 339104-59-5)
- 3-Methoxy-N-(2-(3-(piperazin-1-ylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)benzamide (CAS 925437-59-8)
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- N1-[4-methoxy-2-(trifluoromethyl)phenyl]-2-[3-chloro-3-(4-chlorophenyl)prop-2-enylidene]hydrazine-1-carbothioamide (CAS 680212-21-9)
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Recommended Standards
- N-(4-((4-((4-(Furan-2-yl)thiazol-2-yl)methyl)piperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 1105237-25-9)
- (S)-2-((S)-2-Amino-3-phenylpropanamido)-5-guanidino-N-(naphthalen-2-yl)pentanamide (CAS 115871-02-8)
- Bis(4-(2-(prop-1-en-1-yl)phenoxy)phenyl)methanone (CAS 109423-33-8)
- 4-(4-(5-(Furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidine-1-carbonyl)-N,N-dimethylbenzenesulfonamide (CAS 1171810-04-0)
- 5,6-Dibromo-1,10-phenanthroline (CAS 56290-06-3)
- 2-(Pyridin-3-yl)cyclopropanamine (CAS 859238-90-7)
- 1-(tert-Butoxycarbonyl)-4-(4-fluorophenyl)piperidine-4-carboxylic acid 644981-89-5 9879AB C17H22FNO4 (CAS 644981-89-5)
- N-benzyl-2-chloro-6-methylpyrimidine-4-carboxamide (CAS 1344702-15-3)
- 4,5-Dimethoxy-2-(2-methylpropanamido)benzoic acid (CAS 405898-41-1)
- 2-(Diphenylamino)benzoic acid (CAS 17626-44-7)
- 1-(Thiophen-2-yl)prop-2-en-1-ol (CAS 393148-57-7)
- Methyl (2-fluorophenoxy)acetate (CAS 449808-45-1)
- Ethyl(imino)(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-l6-sulfanone (CAS 2870698-21-6)
- Semaglutide Impurity 4 (CAS CATO-C4X-22264)
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